Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Birmingham Greyhound Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Birmingham Greyhound Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Birmingham Greyhound Bus Station | No tags | ||||
 | Bus | 1116 Woodruff Rd | Birmingham Greyhound Bus Station | No tags | ||||
 | Bus | Greenville, (SC - Taqueria Guadalajara #3) | McDonald's - Birmingham | No tags |
Last refresh of the prices: Today at 6:14 PM EST.
Compare 2 ways to go from Greenville to Birmingham
Among the sustainable travel choices, the train stands out as a good way to reach Birmingham. The journey takes about 8 hours 14 minutes, and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Birmingham?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Birmingham
- A
Birmingham Greyhound Bus Station
1801 Morris Ave, 35203 Birmingham, AL - B2427 Acton Rd, Vestavia Hills, AL 35243, USA
Compare bus companies
Frequently asked questions about travelling from Greenville, SC to Birmingham, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Birmingham?
The cheapest bus tickets from Greenville to Birmingham start from $72. The average price for this route is around $118. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Birmingham?
The average bus travel time from Greenville to Birmingham is 7h 15m, covering a distance of 440 km. The quickest bus can get you there in 5h 50m and is operated by FlixBus.
Which bus companies service the Greenville to Birmingham route?
Several major bus companies operate on this route with 7 buses available per day, including services from Tornado Bus, Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Greenville to Birmingham?
The earliest bus departs from Greenville to Birmingham at 8:40am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Birmingham?
A bus trip from Greenville to Birmingham generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Birmingham?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Greenville to Birmingham?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Greenville to Birmingham?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Birmingham?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Birmingham, US was searched and found on Dec 13, 2025 with a price of $71To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Birmingham, US, as early as possible.
You can expect to pay from $71 to $227 for a bus ticket from Greenville, SC to Birmingham, US based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-12-13.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
