Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | 1116 Woodruff Rd | Lafayette Transit System | No tags | ||||
 | Bus | 1116 Woodruff Rd | Lafayette Transit System | No tags | ||||
Greyhound + FlixBus | Bus | 1116 Woodruff Rd | TA Travel Center - Lafayette | No tags | ||||
Greyhound + FlixBus | Bus | 1116 Woodruff Rd | Lafayette Transit System | No tags | ||||
FlixBus + Greyhound | Bus | 1116 Woodruff Rd | TA Travel Center - Lafayette | No tags |
Compare 2 ways to go from Greenville to Lafayette
Among the sustainable travel choices, the Bus stands out as a good way to reach Lafayette. The journey takes about 18 hours 30 minutes, and with fares starting at just $255, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Lafayette?
Stops in Greenville
Stops in Lafayette
- A1701 N University Ave, Lafayette, LA 70507, USA
- B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501 - C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA
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Frequently asked questions about travelling from Greenville, SC to Lafayette, LA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Lafayette?
The cheapest bus tickets from Greenville to Lafayette start from $255. The average price for this route is around $300. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Lafayette?
The average bus travel time from Greenville to Lafayette is 18h 30m, covering a distance of 1044 km. The quickest bus can get you there in 12h 30m and is operated by Tornado Bus.
Which bus companies service the Greenville to Lafayette route?
Several major bus companies operate on this route with 12 buses available per day, including services from Tornado Bus, Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Greenville to Lafayette?
The earliest bus departs from Greenville to Lafayette at 1:20pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Lafayette?
A bus trip from Greenville to Lafayette generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Lafayette?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Greenville to Lafayette?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 4.1.
Which bus company has the best on-time performance from Greenville to Lafayette?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Lafayette?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Lafayette, LA was searched and found on Jan 16, 2026 with a price of $211To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Lafayette, LA, as early as possible.
What's the cheapest way to go from Greenville, SC to Lafayette, LA?
The Bus is the cheapest travel choice for this destination
