How much is the bus ticket from Greenville to Lafayette?

The cheapest bus tickets from Greenville to Lafayette start from $179. The average price for this route is around $211. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Greenville to Lafayette?

The average bus trip duration from Greenville to Lafayette is 18h 30m, covering a distance of 647 miles (1044 km). The quickest bus can get you there in 12h 30m and is operated by Tornado Bus .

Which bus companies service the Greenville to Lafayette route?

Several major bus companies operate on this route with 12 buses available per day, including services from Tornado Bus , Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Greenville to Lafayette?

The earliest bus departs from Greenville to Lafayette at 1:20pm. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from Greenville to Lafayette?

A bus trip from Greenville to Lafayette generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Greenville to Lafayette?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87500 reviews.

Which bus company has the best Wi-Fi from Greenville to Lafayette?

Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 4.1.

Which bus company has the most timely service from Greenville to Lafayette?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Greenville to Lafayette?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus , with a cleanliness rating of 4.5 out of 5 stars.

Bus Greenville to Lafayette from $179 | Refundable Tickets

Previously seen trips

Next departures for Greenville to Lafayette on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	12:55pm	1116 Woodruff Rd	15h 50m	3:45am	Lafayette Transit System	No tags
	Bus	3:30pm	1116 Woodruff Rd	18h 35m	9:05am	Lafayette Transit System	No tags
Greyhound + FlixBus	Bus	3:30pm	1116 Woodruff Rd	19h 45m	10:15am	TA Travel Center - Lafayette	No tags
Greyhound + FlixBus	Bus	7:45pm	1116 Woodruff Rd	18h 5m	12:50pm	Lafayette Transit System	No tags
FlixBus + Greyhound	Bus	7:45pm	1116 Woodruff Rd	20h 20m	3:05pm	TA Travel Center - Lafayette	No tags

Compare 2 ways to go from Greenville to Lafayette

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as the good way to reach Lafayette. The journey takes about 18 hours 30 minutes and with fares starting at just $179, it presents an excellent value for a comfortable ride.

12bus per day

18h 30mAverage Duration

647 milesDistance

26kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$179 - $237	Average Duration18h 30m	CO₂ emissions 26kg CO₂e
Train	Average Price$223 - $223	Average Duration1d 7h	CO₂ emissions 94kg CO₂e

Where are the popular stops in Greenville and Lafayette?

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
Map
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Map

Stops in Lafayette

A
TA Travel Center - Lafayette
1701 N University Ave, Lafayette, LA 70507, USA
Visit page Map
B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501
Map
C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA
Map

Compare bus companies

Tornado Bus

3/5172 reviews

Staff4.7

Timeliness3.3

Cleanliness4.4

Wifi3.9

A Texas-based company, Tornado Bus operates throughout the United States, with routes connecting major cities, including Houston, San Antonio and El Paso. Each day,2 buses leave from their terminals to destinations across the continent. Their buses are equipped with free Wi-Fi, air conditioning, bathrooms, power outlets and a comfortable amount of legroom. With prices as low as $237 for a short ride, Tornado offers options for budget travelers, without compromising comfort. and those looking for a little luxury. The company requires printed tickets for boarding and their tickets are non-refundable, but you can exchange them up to two hours before travel time for a fee. With a friendly staff and multiple routes, traveling with Tornado is a convenient way to get around.

Greyhound

3.5/587,504 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/512,073 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Greenville, SC to Lafayette, LA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Greenville to Lafayette?
The cheapest bus tickets from Greenville to Lafayette start from $179. The average price for this route is around $211. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Lafayette?
The average bus trip duration from Greenville to Lafayette is 18h 30m, covering a distance of 647 miles (1044 km). The quickest bus can get you there in 12h 30m and is operated by Tornado Bus.
Which bus companies service the Greenville to Lafayette route?
Several major bus companies operate on this route with 12 buses available per day, including services from Tornado Bus, Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Greenville to Lafayette?
The earliest bus departs from Greenville to Lafayette at 1:20pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Lafayette?
A bus trip from Greenville to Lafayette generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Greenville to Lafayette?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Greenville to Lafayette?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 4.1.
Which bus company has the most timely service from Greenville to Lafayette?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Lafayette?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/15

No data

01/16

$148

Today

No data

01/18

No data

01/19

No data

01/20

No data

01/21

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01/22

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The cheapest trip from Greenville, SC to Lafayette, LA was searched and found on Jan 16, 2026 with a price of $148

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Lafayette, LA, as early as possible.