Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Knoxville Bus Station | Downtown Transit Center | No tags | ||||
 | Bus | Knoxville Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Knoxville Bus Station | Downtown Transit Center | No tags | ||||
| Bus | Knoxville Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Knoxville Bus Station | Downtown Transit Center | No tags |
Get from Knoxville to Indianapolis
The journey takes about 14 hours 15 minutes, and with fares starting at just $128, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Indianapolis?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87468 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $129
Greyhound Knoxville Indianapolis recent customer reviews
Was a nice experience, will go greyhound again
Kimberly L.
Frequently asked questions about travelling from Knoxville, TN to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Indianapolis?
The cheapest bus tickets from Knoxville to Indianapolis start from $128. The average price for this route is around $206. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Indianapolis?
The average bus travel time from Knoxville to Indianapolis is 14h 15m, covering a distance of 465 km. The quickest bus can get you there in 10h 35m and is operated by Greyhound.
Which bus companies service the Knoxville to Indianapolis route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Knoxville to Indianapolis?
The earliest bus departs from Knoxville to Indianapolis at 6:10pm. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Knoxville to Indianapolis?
A bus trip from Knoxville to Indianapolis generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Indianapolis was searched and found on Jan 4, 2026 with a price of $155To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Indianapolis, as early as possible.
You can expect to pay from $155 to $157 for a bus ticket from Knoxville, TN to Indianapolis based on the last 0 days. You can expect to find the cheapest price for the trip at $155 which is on 2026-01-04.
