Next departures for Lafayette to San Antonio on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
CheapestFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Valley Transit
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
FlixBus + Valley Transit
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines Mexico
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
No tags
Next departures for Lafayette to San Antonio on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
CheapestFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
No tags
FlixBus + Valley Transit
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
No tags
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
Next departures for Lafayette to San Antonio on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
CheapestFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
FlixBus + Valley Transit
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines Mexico
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
No tags
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
Last refresh of the prices: Today at 9:44 AM CST.
Compare 2 ways to go from Lafayette to San Antonio
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 8 hours 45 minutes, and with fares starting at just $77, it presents an excellent value for a comfortable ride.
Based on 87382 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $98
Based on 11380 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $77
Frequently asked questions about travelling from Lafayette, LA to San Antonio, US by bus
What is the distance between Lafayette and San Antonio?
Lafayette and San Antonio are 632 km (392 miles) apart.
What are the departure and arrival locations for buses traveling from Lafayette to San Antonio?
Buses departing from TA Travel Center - Lafayette in Lafayette will take you to San Antonio Bus Station in San Antonio.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-17
$78
11-18
No data
Today
$144
11-20
No data
11-21
No data
11-22
$91
11-23
No data
11-24
$97
The cheapest trip from Lafayette, LA to San Antonio, US was searched and found on Nov 17, 2025 with a price of $78
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to San Antonio, US, as early as possible.
You can expect to pay from $78 to $165 for a bus ticket from Lafayette, LA to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-11-22.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Lafayette, LA to San Antonio, US was searched and found on Nov 17, 2025 with a price of $78
