Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | TA Travel Center - Lafayette | San Antonio Bus Station | CheapestFastest | ||||
Greyhound Lines, Inc. + Greyhound Lines Mexico | Bus | Lafayette Transit System | San Antonio Bus Station | No tags | ||||
Greyhound Lines, Inc. + Valley Transit | Bus | Lafayette Transit System | San Antonio Bus Station | No tags | ||||
FlixBus + Valley Transit | Bus | TA Travel Center - Lafayette | San Antonio Bus Station | No tags | ||||
FlixBus + Greyhound Lines Mexico | Bus | TA Travel Center - Lafayette | San Antonio Bus Station | No tags |
Last refresh of the prices: Yesterday at 09:44 CST.
Compare 2 ways to travel from Lafayette to San Antonio
Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 8 hours 45 minutes and with fares starting at just £42, it presents an excellent value for a comfortable ride.
Compare bus companies
Where are the popular stops in Lafayette and San Antonio?
Stops in Lafayette
- A1701 N University Ave, Lafayette, LA 70507, USA
- B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501 - C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C165 Bowie St, San Antonio, 78205
- D4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Frequently asked questions about travelling by bus from Lafayette, LA to San Antonio, US
How far is San Antonio from Lafayette by coach?
The journey from Lafayette to San Antonio by coach covers an approximate distance of 392 miles (632 km).
What is the best way to go from Lafayette to San Antonio without flying?
To travel from Lafayette to San Antonio without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lafayette, LA to San Antonio, US was searched and found on 22 Nov 2025 with a price of £50To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to San Antonio, US as early as possible.
You can expect to pay from £50 to £90 for a bus ticket from Lafayette, LA to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at £50, which is on 2025-11-22.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
