Next departures for Lafayette to San Antonio on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Transit System
San Antonio Bus Station
CheapestFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
FlixBus + Valley Transit
Bus
TA Travel Center - Lafayette
San Antonio Bus Station
No tags
Bus
Lafayette Transit System
San Antonio Bus Station
No tags
Last refresh of the prices: Yesterday at 7:58 AM CST.
Compare 2 ways to go from Lafayette to San Antonio
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 8 hours 45 minutes and with fares starting at just $54, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Lafayette, LA to San Antonio, US by bus
What is the distance between Lafayette and San Antonio?
The distance between the two cities is 392 miles (632 km).
What are the departure and arrival stations when taking the bus from Lafayette to San Antonio?
If you're headed to San Antonio from Lafayette, chances are that your bus will depart from TA Travel Center - Lafayette and arrive at San Antonio Bus Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in San Antonio?
Once in San Antonio, you can start exploring the city and discover its surroundings. The top sights and things to do are Japanese Tea Garden, Morgan's Wonderland Ultra-Accessible Fun Park, La Villita Historic Arts Village, Tower of the Americas and Traders Village.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$59
11/17
$54
Today
No data
11/19
$100
11/20
No data
11/21
No data
11/22
$61
11/23
No data
The cheapest trip from Lafayette, LA to San Antonio, US was searched and found on Nov 17, 2025 with a price of $54
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to San Antonio, US, as early as possible.
You can expect to pay from $54 to $101 for a bus ticket from Lafayette, LA to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2025-11-22.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Lafayette, LA to San Antonio, US was searched and found on Nov 17, 2025 with a price of $54
