Bus Tickets from Louisville to Columbia, MO

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TodayAug 1
from US$89
TomorrowAug 2
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Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 2 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 1 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 1 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 2 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 2 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Sunday at 9:58 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Louisville to Columbia, MO: Trip Overview

Average Ticket PriceUS$90
Average Bus Trip Duration17h 30m
Number of daily buses7
Earliest bus departure8:00am
Distance575 km
Latest bus departure10:55pm

Louisville to Columbia Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Louisville to Columbia.

We make sure you can find a bus service from Louisville to Columbia from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Louisville to Columbia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Louisville - Columbia, MO

  1. What is the travel distance from Louisville to Columbia?

    Louisville and Columbia are 578 km (358 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Louisville to Columbia?

    Buses departing from Louisville Greyhound Bus Station in Louisville will take you to Midway Truck Plaza Bus Stop in Columbia.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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Today
US$82
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busbud logoThe cheapest trip from Louisville to Columbia, MO was searched and found on Aug 1, 2025 with a price of US$82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Columbia, MO, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Louisville to Columbia but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Louisville to Columbia, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Louisville to Columbia that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Louisville to Columbia while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Louisville by bus?

Bus from Louisville to Columbia, MO

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