Bus Tickets from Louisville to Columbia, MO

TodayJul 30
TomorrowJul 31
FriAug 1
from $89
SatAug 2
SunAug 3
MonAug 4
TueAug 5
WedAug 6

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 2 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 1 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 1 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 2 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Louisville
    Departure location: Louisville, KY
    Arrival time: August 2 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Louisville to Columbia, MO: Trip Overview

Average ticket price$90
Average bus trip duration17h 30m
Number of daily buses7
Earliest bus departure8:00am
Distance357 miles (575 km)
Latest bus departure10:55pm

Louisville to Columbia Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Louisville to Columbia.

We make sure you can find a bus service from Louisville to Columbia from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Louisville to Columbia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Louisville - Columbia, MO

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/28
No data
07/29
No data
Today
No data
07/31
No data
08/01
$82
08/02
No data
08/03
No data
08/04
No data
busbud logoThe cheapest trip from Louisville to Columbia, MO was searched and found on Aug 1, 2025 with a price of $82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Columbia, MO, as early as possible.

You can expect to pay from $82 to $122 for a bus ticket from Louisville to Columbia, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $82 which is on 2025-08-01.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Louisville to Columbia but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Louisville to Columbia, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Louisville to Columbia that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Louisville to Columbia while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Louisville by bus?

Bus from Louisville to Columbia, MO

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌