Next departures for Madrid to Santander on April 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Madrid-Chamartin
Santander
Fastest
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on April 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Madrid-Chamartin
Santander
CheapestFastest
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Next departures for Madrid to Santander on April 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Madrid-Chamartin
Santander
Cheapest
Madrid-Chamartin
Santander
Fastest
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on April 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Madrid-Chamartin
Santander
Cheapest
Madrid-Chamartin
Santander
Fastest
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on April 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
Fastest
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Next departures for Madrid to Santander on April 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Madrid-Chamartin
Santander
CheapestFastest
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Next departures for Madrid to Santander on April 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Avenida de América Metro
Santander (Estacion de Autobuses)
Cheapest
Madrid-Chamartin
Santander
Fastest
Avenida de América Metro
Santander (Estacion de Autobuses)
No tags
Madrid-Chamartin
Santander
No tags
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)
No tags
Last refresh of the prices: Today at 12:25 AM CEST.
Compare 2 ways to go from Madrid to Santander
We recommend taking the train
Among the sustainable travel choices, the Train stands out as a good way to reach Santander. The journey takes about 4 hours 21 minutes, and with fares starting at just CZK 550, it presents an excellent value for a comfortable ride.
According to 77 reviews, ALSA received a 4.3-star rating for this journey. Travellers were especially satisfied with the temperature and the departure location, but some complained about the Wi‑Fi. ALSA ticket prices on this trip start at CZK 1,088
ALSA Madrid Santander recent customer reviews
Alsa in general is very reliable and punctual. I have taken an Alsa bus a few times and enjoy it every time. Kudos for this company.
5.0 out of 5 stars
Penelope M.
Bus drivers very unfriendly, would not adjust sunscreen when sun was behind us and did not interfere with his view. Ade people run after the bus, when he knew they where running to catch up, his smile. Informed he just wanted to give them a hard time, not good pr
Based on 984 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the staff and the temperature but often complained with the Wi‑Fi. Renfe ticket prices on this trip start at CZK 550
Based on 12521 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at CZK 1,061
Frequently asked questions about travelling from Madrid to Santander by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Madrid to Santander?
The cheapest tickets from Madrid to Santander start at CZK 550. The average price for this route is around CZK 1,078. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Madrid to Santander?
The average trip duration from Madrid to Santander is 4h 55m, covering a distance of 333 km. The quickest vehicle can get you there in 4h 20m and is operated by Renfe.
Which companies service the Madrid to Santander route?
Several major companies operate on this route with 8 trips available per day, including services from ALSA, FlixBus, Renfe.
What is the earliest and latest departure time from Madrid to Santander?
The earliest trip from Madrid to Santander departs at 12:30am. And the latest trip departs at 11:30pm.
What are the CO₂ emissions for the trip from Madrid to Santander?
A trip from Madrid to Santander generates an estimated 8.3172 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Madrid to Santander?
According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61718 reviews.
Which company has the best Wi-Fi from Madrid to Santander?
Based on Busbud reviews, the company ALSA has the highest Wi‑Fi rating with a score of 3.5.
Which company has the most on-time service from Madrid to Santander?
According to Busbud traveller reviews, the most punctual company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which company has the cleanest vehicles from Madrid to Santander?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
04-22
CZK 618
04-23
CZK 1,048
Today
CZK 1,047
04-25
CZK 464
04-26
CZK 464
04-27
CZK 776
04-28
CZK 930
04-29
CZK 465
The cheapest trip from Madrid to Santander was searched and found on Apr 25, 2026 with a price of CZK 464
To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Madrid to Santander, as early as possible.
You can expect to pay between CZK 464 and CZK 2,048 for a bus or train ticket from Madrid to Santander based on the past 2 days. You can expect to find the lowest price for this trip at CZK 464 on 2026-04-25.
Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.