Bus Tickets from Madrid to Santander

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TodayJun 14
from US$54
TomorrowJun 15
from US$52
MonJun 16
from US$49
TueJun 17
from US$49
WedJun 18
from US$49
ThuJun 19
from US$52
FriJun 20
from US$49
SatJun 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 15 at
    Departure city: Madrid
    Departure location: Avenida de América Metro
    Arrival time: June 15 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: ALSAALSA
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 15 at
    Departure city: Madrid
    Departure location: Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
    Arrival time: June 16 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: ALSAALSA
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Madrid
    Departure location: Avenida de América Metro
    Arrival time: June 15 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: ALSA SupraALSA Supra
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Madrid
    Departure location: Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
    Arrival time: June 15 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: ALSAALSA
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Madrid
    Departure location: Madrid (South)
    Arrival time: June 16 at
    Destination city: Santander
    Destination location: Santander (Estacion de Autobuses)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 4:06 AM CEST.

Prices and availability are subject to change.

Accepted payments

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Compare 3 ways to go from Madrid to Santander

Average PriceUS$47 - US$147Average Duration5h 30m
8kg CO₂e5 out of 5 stars
Most eco-friendly
Average PriceUS$25 - US$94Average Duration4h 21m
8kg CO₂e5 out of 5 stars
Fastest
Carpool
Average PriceUS$19 - US$57Average Duration4h 30m
14kg CO₂e4 out of 5 stars
Cheapest
busbud logoBusbud recommends carpooling from Madrid to Santander

Among the sustainable travel choices, the carpool stands out as a good way to reach Santander. The journey takes about 4 hours 30 minutes, and with fares starting at just US$19, it presents an excellent value for a comfortable ride.

20.347826086956523carpool per day
4h 30mAverage Duration
US$19Cheapest ticket
14kgCO₂ emissions

Bus Madrid to Santander: Trip Overview

Average Ticket PriceUS$52
Average Bus Trip Duration5h 30m
Number of daily buses14
Earliest bus departure12:30am
Distance336 km
Latest bus departure11:30pm

Madrid to Santander Bus

With Busbud, comparing and booking tickets for a bus from Madrid to Santander is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Madrid to Santander.

Discover how much the bus trip from Madrid to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Madrid - Santander

  1. How long is the bus ride from Madrid to Santander?

    The trip from Madrid to Santander will take on average 5h 30m. The fastest bus on this trip will get to Santander in 5h 15m

  2. How far is Madrid from Santander?

    Madrid and Santander are 340 km (211 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Madrid to Santander?

    Buses departing from Estación Sur in Madrid will take you to Calle Navas de Tolosa, 2 in Santander.

  4. How much does it cost to take the bus from Madrid to Santander?

    The bus from Madrid to Santander will cost you US$52, on average.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-12
US$48
06-13
US$115
Today
US$48
06-15
US$46
06-16
US$43
06-17
US$43
06-18
US$43
06-19
US$46
busbud logoThe cheapest trip from Madrid to Santander was searched and found on Jun 16, 2025 with a price of US$43

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Santander, as early as possible.

You can expect to pay from US$43 to US$127 for a bus ticket from Madrid to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at US$43 which is on 2025-06-16.

Usually Flixbus (ES), ALSA Supra will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Madrid to Santander.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Madrid to Santander.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Madrid to Santander will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Madrid to Santander.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Madrid by bus?

Bus from Madrid to Santander

You can also go to Santander by train

Train from Madrid to Santander

Why choose Busbud?

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Popular Buses Connecting Madrid

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Popular Buses Connecting Santander

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