Bus and Train from Madrid to Santander: Tickets & Schedules

Next available departures

Next departures for Madrid to Santander on April 24
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSA
Avenida de América Metro
Santander (Estacion de Autobuses)Cheapest
RENFE Alvia
Madrid-Chamartin
SantanderFastest
ALSA Supra
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)No tags
RENFE Alvia
Madrid-Chamartin
SantanderNo tags
ALSA
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)No tags

Last refresh of the prices: Today at 12:25 AM CEST.

Compare 2 ways to go from Madrid to Santander

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Santander. The journey takes about 4 hours 21 minutes, and with fares starting at just CZK 550, it presents an excellent value for a comfortable ride.

2train per day
4h 21mAverage Duration
333 kmDistance
8kgCO₂ emissions
Average PriceCZK 1,088 - CZK 1,633Average Duration5h 30m
8kg CO₂e
Average PriceCZK 550 - CZK 2,259Average Duration4h 21m
8kg CO₂e

Frequently asked questions about travelling from Madrid to Santander by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is a ticket from Madrid to Santander?

    The cheapest tickets from Madrid to Santander start at CZK 550. The average price for this route is around CZK 1,078. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.

  2. How long is the ride from Madrid to Santander?

    The average trip duration from Madrid to Santander is 4h 55m, covering a distance of 333 km. The quickest vehicle can get you there in 4h 20m and is operated by Renfe.

  3. Which companies service the Madrid to Santander route?

    Several major companies operate on this route with 8 trips available per day, including services from ALSA, FlixBus, Renfe.

  4. What is the earliest and latest departure time from Madrid to Santander?

    The earliest trip from Madrid to Santander departs at 12:30am. And the latest trip departs at 11:30pm.

  5. What are the CO₂ emissions for the trip from Madrid to Santander?

    A trip from Madrid to Santander generates an estimated 8.3172 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best company from Madrid to Santander?

    According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61718 reviews.

  7. Which company has the best Wi-Fi from Madrid to Santander?

    Based on Busbud reviews, the company ALSA has the highest Wi‑Fi rating with a score of 3.5.

  8. Which company has the most on-time service from Madrid to Santander?

    According to Busbud traveller reviews, the most punctual company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.

  9. Which company has the cleanest vehicles from Madrid to Santander?

    According to Busbud traveller reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-22
CZK 618
04-23
CZK 1,048
Today
CZK 1,047
04-25
CZK 464
04-26
CZK 464
04-27
CZK 776
04-28
CZK 930
04-29
CZK 465
busbud logoThe cheapest trip from Madrid to Santander was searched and found on Apr 25, 2026 with a price of CZK 464

To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Madrid to Santander, as early as possible.

You can expect to pay between CZK 464 and CZK 2,048 for a bus or train ticket from Madrid to Santander based on the past 2 days. You can expect to find the lowest price for this trip at CZK 464 on 2026-04-25.

Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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