Next available departures

Next departures for Madrid to Santander on September 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Wi‑Fi Toilet Power outlets	7:08pm	Madrid-Chamartin	4h 4m	11:12pm	Santander	CheapestFastest

Next departures for Madrid to Santander on September 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	4:45pm	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	10:15pm	Santander (Estacion de Autobuses)	Cheapest
Wi‑Fi Toilet Power outlets	7:08pm	Madrid-Chamartin	4h 4m	11:12pm	Santander	Fastest
	3:15pm	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 15m	8:30pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	6:45pm	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 15m	12:00am	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	3:00pm	Avenida de América Metro	5h 30m	8:30pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags

Next departures for Madrid to Santander on September 22
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	Cheapest
Wi‑Fi Toilet Power outlets	7:08pm	Madrid-Chamartin	4h 4m	11:12pm	Santander	Fastest
	12:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 45m	6:30am	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	8:15am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 35m	1:50pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags
	10:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	4:15pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags

Next departures for Madrid to Santander on September 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	Cheapest
Wi‑Fi Toilet Power outlets	7:08pm	Madrid-Chamartin	4h 4m	11:12pm	Santander	Fastest
	12:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 45m	6:30am	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	8:15am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 35m	1:50pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags
	10:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	4:15pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags

Next departures for Madrid to Santander on September 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	8:00am	Avenida de América Metro	5h 50m	1:50pm	Santander (Estacion de Autobuses)	Cheapest
Wi‑Fi Toilet Power outlets	7:08pm	Madrid-Chamartin	4h 4m	11:12pm	Santander	Fastest
	12:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 45m	6:30am	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	8:15am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 35m	1:50pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	10:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	4:15pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags

Next departures for Madrid to Santander on September 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	8:00am	Avenida de América Metro	5h 50m	1:50pm	Santander (Estacion de Autobuses)	Cheapest
Wi‑Fi Toilet Power outlets	7:08pm	Madrid-Chamartin	4h 4m	11:12pm	Santander	Fastest
	12:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 45m	6:30am	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	8:15am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 35m	1:50pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	10:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	4:15pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags

Next departures for Madrid to Santander on September 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	Cheapest
Wi‑Fi Toilet Power outlets	7:08pm	Madrid-Chamartin	4h 4m	11:12pm	Santander	Fastest
	12:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 45m	6:30am	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	7:41am	Madrid-Chamartin	4h 9m	11:50am	Santander	No tags
	10:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	4:15pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags
	1:15pm	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 15m	6:30pm	Santander (Estacion de Autobuses)	No tags
Wi‑Fi Toilet Power outlets	1:40pm	Madrid-Chamartin	4h 7m	5:47pm	Santander	No tags

Next departures for Madrid to Santander on September 27
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
10:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	4:15pm	Santander (Estacion de Autobuses)	Cheapest
3:15pm	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 15m	8:30pm	Santander (Estacion de Autobuses)	Fastest
12:45am	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 45m	6:30am	Santander (Estacion de Autobuses)	No tags
4:45pm	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 30m	10:15pm	Santander (Estacion de Autobuses)	No tags
6:45pm	Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4	5h 15m	12:00am	Santander (Estacion de Autobuses)	No tags
12:30am	Avenida de América Metro	6h	6:30am	Santander (Estacion de Autobuses)	No tags
10:30am	Avenida de América Metro	5h 45m	4:15pm	Santander (Estacion de Autobuses)	No tags
3:00pm	Avenida de América Metro	5h 30m	8:30pm	Santander (Estacion de Autobuses)	No tags

Last refresh of the prices: Today at 4:48 PM CEST.

Compare 2 ways to go from Madrid to Santander

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Santander. The journey takes about 4 hours 7 minutes, and with fares starting at just ZAR 432, it presents an excellent value for a comfortable ride.

3train per day

4h 7mAverage Duration

333 kmDistance

8kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceZAR 887 - ZAR 1,317	Average Duration5h 30m	CO₂ emissions 8kg CO₂e
Train	Average PriceZAR 432 - ZAR 1,880	Average Duration4h 7m	CO₂ emissions 8kg CO₂e

Bus stations and stops in Madrid and Santander

Stops in Madrid

A
Madrid-Chamartin
C. de la Hiedra, 5, 28036 Madrid, Spain
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B
Madrid Puerta De Atocha
Madrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
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C
Madrid-Príncipe Pio
Príncipe Pío, 28008 Madrid, Spain
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D
Madrid-Barajas Airport
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E
Nuevos Ministerios
Estación de Nuevos Ministerios, 28046 Madrid, Spain
F
Avenida de América Metro
Avenida de América, 9, 28002 Madrid, Spain
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Stops in Santander

A
Calle Navas de Tolosa, 2
Calle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
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B
Santander Airport
Visit page
C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain
D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain
E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain
F
Estación Marítima
39002 Santander, Cantabria, Spain

Compare companies

ALSA

4.3/563,753 reviews

Staff4.7

Timeliness4.3

Cleanliness4.7

Wi‑Fi3.5

According to 78 reviews, ALSA received a 4.3-star rating for this journey. Travellers were especially satisfied with the temperature and the departure location, but some complained about the Wi‑Fi. ALSA ticket prices on this trip start at ZAR 887

ALSA Madrid Santander recent customer reviews

Alsa in general is very reliable and punctual. I have taken an Alsa bus a few times and enjoy it every time. Kudos for this company.

Penelope M.

August 30, 2018

Bus drivers very unfriendly, would not adjust sunscreen when sun was behind us and did not interfere with his view. Ade people run after the bus, when he knew they where running to catch up, his smile. Informed he just wanted to give them a hard time, not good pr

Barbara D.

October 12, 2017

Great experience. Good driver. On time.

Aracelis B.

October 21, 2024

Renfe

4.1/51,071 reviews

Staff4.7

Timeliness4.1

Cleanliness4.5

Wi‑Fi3.0

FlixBus

3.5/515,795 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

Companies in ES:FlixBus, Renfe, BlaBlaCar Bus, FlixTrain, ALSA, Iryo, Rede Expressos, El Expreso de Canfranc, Sindbad, Avanza, BlaBlaCar Bus - Alsa

Frequently asked questions about travelling from Madrid to Santander by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Madrid to Santander?
The cheapest tickets from Madrid to Santander start at ZAR 432. The average price for this route is around ZAR 856. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Madrid to Santander?
The average trip duration from Madrid to Santander is 4h 48m, covering a distance of 333 km. The quickest vehicle can get you there in 4h 4m and is operated by Renfe.
Which companies service the Madrid to Santander route?
Several major companies operate on this route with 8 trips available per day, including services from ALSA, FlixBus, Renfe.
What is the earliest and latest departure time from Madrid to Santander?
The earliest trip from Madrid to Santander departs at 12:30am. And the latest trip departs at 11:45pm.
What are the CO₂ emissions for the trip from Madrid to Santander?
A trip from Madrid to Santander generates an estimated 8.3176125 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Madrid to Santander?
According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 63701 reviews.
Which company has the best Wi-Fi from Madrid to Santander?
Based on Busbud reviews, the company ALSA has the highest Wi‑Fi rating with a score of 3.5.
Which company has the most on-time service from Madrid to Santander?
According to Busbud traveller reviews, the most punctual company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which company has the cleanest vehicles from Madrid to Santander?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09-18

ZAR 802

09-19

ZAR 803

Today

ZAR 803

09-21

ZAR 803

09-22

ZAR 703

09-23

ZAR 587

09-24

ZAR 713

09-25

ZAR 774

The cheapest trip from Madrid to Santander was searched and found on Sep 23, 2026 with a price of ZAR 587

To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Madrid to Santander, as early as possible.

You can expect to pay between ZAR 587 and ZAR 1,783 for a bus or train ticket from Madrid to Santander based on the past 2 days. You can expect to find the lowest price for this trip at ZAR 587 on 2026-09-23.

Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.