Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Avenida de América Metro | Santander (Estacion de Autobuses) | Cheapest | |||||
| Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Santander (Estacion de Autobuses) | Fastest | |||||
 | Avenida de América Metro | Santander (Estacion de Autobuses) | No tags | |||||
| Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Santander (Estacion de Autobuses) | No tags | |||||
| Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Santander (Estacion de Autobuses) | No tags |
Last refresh of the prices: Today at 7:22 AM CEST.
Compare 2 ways to go from Madrid to Santander
Among the sustainable travel choices, the Train stands out as a good way to reach Santander. The journey takes about 4 hours 21 minutes, and with fares starting at just $37, it presents an excellent value for a comfortable ride.
Where are the popular stops in Madrid and Santander?
Stops in Madrid
- AC. de la Hiedra, 5, 28036 Madrid, Spain
- BMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
- CPríncipe Pío, 28008 Madrid, Spain
- E
Nuevos Ministerios
Estación de Nuevos Ministerios, 28046 Madrid, Spain - FAvenida de América, 9, 28002 Madrid, Spain
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Compare companies
Frequently asked questions about travelling from Madrid to Santander by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Madrid to Santander?
The cheapest tickets from Madrid to Santander start at $37. The average price for this route is around $71. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Madrid to Santander?
The average trip duration from Madrid to Santander is 4h 55m, covering a distance of 332 km. The quickest vehicle can get you there in 4h 20m and is operated by Renfe.
Which companies service the Madrid to Santander route?
What is the earliest and latest departure time from Madrid to Santander?
The earliest trip from Madrid to Santander departs at 12:30am. And the latest trip departs at 11:30pm.
What are the CO₂ emissions for the trip from Madrid to Santander?
A trip from Madrid to Santander generates an estimated 8.2813125 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Madrid to Santander?
According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61661 reviews.
Which company has the best Wi-Fi from Madrid to Santander?
Based on Busbud reviews, the company ALSA has the highest Wi‑Fi rating with a score of 3.5.
Which company has the most on-time service from Madrid to Santander?
According to Busbud traveller reviews, the most punctual company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which company has the cleanest vehicles from Madrid to Santander?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madrid to Santander was searched and found on Apr 15, 2026 with a price of $31To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Madrid to Santander, as early as possible.
You can expect to pay between $31 and $126 for a bus or train ticket from Madrid to Santander based on the past 2 days. You can expect to find the lowest price for this trip at $31 on 2026-04-19.
Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
