Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Manchester Airport | Gateway Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Veterans Memorial Park | Gateway Station | No tags |
Last refresh of the prices: Last Tuesday at 8:52 PM EST.
Get from Manchester to St. Louis
The journey takes about 1 day, 9 hours 5 minutes, and with fares starting at just $237, it presents an excellent value for a comfortable ride.
Where are the popular stops in Manchester and St. Louis?
Stops in Manchester
- AAirport Terminal, 1 Airport Rd, Manchester, NH 03103, USA
- B
Transportation Center
119 Canal St, Manchester, NH 03101
Compare bus companies
Based on 87468 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $237
Frequently asked questions about travelling from Manchester, NH, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Manchester to St. Louis?
The cheapest bus tickets from Manchester to St. Louis start from $237. The average price for this route is around $413. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Manchester to St. Louis?
The average bus travel time from Manchester to St. Louis is 1d 9h, covering a distance of 1647 km. The quickest bus can get you there in 1d 10h and is operated by Greyhound.
Which bus companies service the Manchester to St. Louis route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Manchester to St. Louis?
The earliest bus departs from Manchester to St. Louis at 6:05am. And the latest bus departs at 3:35pm.
What are the CO₂ emissions for the bus trip from Manchester to St. Louis?
A bus trip from Manchester to St. Louis generates an estimated 41 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Manchester, NH, US to St. Louis was searched and found on Jan 1, 2026 with a price of $186To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Manchester, NH, US to St. Louis, as early as possible.
