Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Memphis Bus Station | Des Moines | Cheapest | ||||
 | Bus | Airways Transit Center | Des Moines | Fastest |
Last refresh of the prices: 2026-01-28 CST.
Get from Memphis to Des Moines
The journey takes about 19 hours 55 minutes, and with fares starting at just $139, it presents an excellent value for a comfortable ride.
Where are the popular stops in Memphis and Des Moines?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
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Frequently asked questions about travelling from Memphis, TN to Des Moines by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Memphis to Des Moines?
The cheapest bus tickets from Memphis to Des Moines start from $139. The average price for this route is around $187. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Memphis to Des Moines?
The average bus travel time from Memphis to Des Moines is 19h 55m, covering a distance of 795 km. The quickest bus can get you there in 14h 40m and is operated by Jefferson Lines.
Which bus companies service the Memphis to Des Moines route?
Several major bus companies operate on this route with 1 buses available per day, including services from Jefferson Lines, Greyhound.
What are the earliest and latest departure times for the bus from Memphis to Des Moines?
The earliest bus departs from Memphis to Des Moines at 8:30am. And the latest bus departs at 6:40pm.
What are the CO₂ emissions for the bus trip from Memphis to Des Moines?
A bus trip from Memphis to Des Moines generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Memphis to Des Moines?
According to Busbud customers, the highest-rated bus company on this route is Jefferson Lines, with an average rating of 3.9 out of 5 stars based on 766 reviews.
Which bus company has the best Wi-Fi from Memphis to Des Moines?
Based on Busbud reviews, the bus company Greyhound has the highest Wi-Fi rating with a score of 2.5.
Which bus company has the best on-time performance from Memphis to Des Moines?
According to Busbud traveller reviews, the most punctual bus company on this route is Jefferson Lines, with a punctuality rating of 3.7 out of 5 stars.
Which bus company has the cleanest buses from Memphis to Des Moines?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Jefferson Lines, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Memphis, TN to Des Moines was searched and found on Feb 6, 2026 with a price of $158To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Memphis, TN to Des Moines, as early as possible.
You can expect to pay from $158 to $219 for a bus ticket from Memphis, TN to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $158 which is on 2026-02-06.
Usually Jefferson Lines, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
