Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
Greyhound + FlixBus | Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
| Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
| Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
Greyhound + FlixBus | Mesa Bus Stop | 1116 Woodruff Rd | No tags |
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Get from Mesa to Greenville
This route is served by bus onlyThe journey takes about 1 day, 22 hours 45 minutes, and with fares starting at just US$233, it presents an excellent value for a comfortable ride.
Bus Mesa to Greenville, SC: Trip Overview
Compare bus companies
Based on 87342 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$268
Mesa to Greenville Bus
Busbud helps you find a bus from Mesa to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Mesa to Greenville will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Mesa to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Mesa and Greenville?
Frequently asked questions on the trip Mesa - Greenville, SC
What is the distance between Mesa and Greenville?
The distance between Mesa and Greenville is approximately 2709 km (1680 miles).
What are the departure and arrival locations for buses traveling from Mesa to Greenville?
Buses departing from Mesa Bus Station in Mesa will take you to Guadalajara Supermarket Bus Stop in Greenville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to Greenville, SC was searched and found on Oct 29, 2025 with a price of US$270To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to Greenville, SC, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mesa and Greenville!
Much more than a mere vehicle taking you from Mesa to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mesa to Greenville that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mesa to Greenville.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top travelled bus routes
Why choose Busbud?
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Mesa
Buses Leaving from Mesa
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Buses Going to Mesa
Popular Buses Connecting Greenville
Buses Leaving from Greenville
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Buses Going to Greenville
- Bus from Atlanta to Greenville
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Popular routes in this country
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