Find coaches from Mesa to Greenville, SC

Previously seen journeys

Next departures from Mesa to Greenville on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Mesa Bus Stop
1116 Woodruff RdNo tags
Greyhound + FlixBus
Mesa Bus Stop
1116 Woodruff RdNo tags
Greyhound
Mesa Bus Stop
1116 Woodruff RdNo tags
Greyhound
Mesa Bus Stop
1116 Woodruff RdNo tags
Greyhound + FlixBus
Mesa Bus Stop
1116 Woodruff RdNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Get from Mesa to Greenville

busbud logoThis route is served by bus only

The journey takes about 1 day, 22 hours 45 minutes, and with fares starting at just US$233, it presents an excellent value for a comfortable ride.

3bus per day
1d 22hAverage duration
1683 milesDistance
68kgCO₂ emissions

Bus Mesa to Greenville, SC: Trip Overview

Average ticket priceUS$265
Average bus trip duration1d 22h
Number of daily buses3
Earliest bus departure07:40
Distance1683 miles
Latest bus departure20:10

Mesa to Greenville Bus

Busbud helps you find a bus from Mesa to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Mesa to Greenville will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Mesa to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Mesa - Greenville, SC

  1. How far is Greenville from Mesa by coach?

    The journey from Mesa to Greenville by coach covers an approximate distance of 1680 miles (2709 km).

  2. What is the best way to go from Mesa to Greenville without flying?

    To travel from Mesa to Greenville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
No data
29/10
US$270
Today
No data
31/10
No data
01/11
No data
02/11
No data
03/11
No data
04/11
No data
busbud logoThe cheapest trip from Mesa to Greenville, SC was searched and found on 29 Oct 2025 with a price of US$270

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to Greenville, SC as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mesa and Greenville!

Much more than a mere vehicle taking you from Mesa to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mesa to Greenville that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mesa to Greenville.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Mesa by bus?

Bus from Greenville, SC to Mesa

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Mesa

Buses Leaving from Mesa

Buses Going to Mesa

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville