Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
Greyhound + FlixBus | Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
| Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
| Mesa Bus Stop | 1116 Woodruff Rd | No tags | |||||
Greyhound + FlixBus | Mesa Bus Stop | 1116 Woodruff Rd | No tags |
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Get from Mesa to Greenville
This route is served by bus onlyThe journey takes about 1 day, 22 hours 45 minutes and with fares starting at just $233, it presents an excellent value for a comfortable ride.
Bus Mesa to Greenville, SC: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Mesa to Greenville Bus
Busbud helps you find a bus from Mesa to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Mesa to Greenville will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Mesa to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Mesa and Greenville?
Frequently asked questions for your trip Mesa - Greenville, SC
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to Greenville, SC was searched and found on Oct 29, 2025 with a price of $270To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to Greenville, SC, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mesa and Greenville!
Much more than a mere vehicle taking you from Mesa to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mesa to Greenville that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mesa to Greenville.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
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The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Mesa
Buses Leaving from Mesa
- Bus from Mesa to Phoenix
- Bus Mesa - San Diego
- Mesa - Los Angeles
- Bus from Mesa to Madison
- Bus Mesa - Las Vegas
- Mesa - Charlotte
- Bus from Mesa to Tucson
- Bus Mesa - Flagstaff
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- Bus from Mesa to Huntsville
- Bus Mesa - Reno
- Mesa - Las Cruces
- Bus from Mesa to Seattle
- Bus Mesa - Superior
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Buses Going to Mesa
Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
- Bus Greenville - Charleston
- Greenville - Spartanburg
- Bus from Greenville to Greensboro
- Bus Greenville - Miami
- Greenville - Chicago
- Bus from Greenville to Charlotte
- Bus Greenville - Atlanta
- Greenville - New York City
- Bus from Greenville to Knoxville
- Bus Greenville - Tarboro
- Greenville - Orlando
- Bus from Greenville to Macon
- Bus Greenville - Dallas
- Greenville - Anderson
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Bus Burlington - Greenville
- Nashville - Greenville
- Bus from Knoxville to Greenville
- Bus Savannah - Greenville
- Orlando - Greenville
- Bus from Charlotte to Greenville
- Bus Charleston - Greenville
- Anderson - Greenville
- Bus from New York City to Greenville
- Bus Asheville - Greenville
- Miami - Greenville
- Bus from Spartanburg to Greenville
- Bus Raleigh - Greenville
- Myrtle Beach - Greenville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
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- Miami - Tampa
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- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio