Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Bus Station | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | Bus Station | Downtown Greyhound Station | Fastest | ||||
| Bus | Bus Station | 537-517 W. Jackson Blvd | No tags |
Last refresh of the prices: Last Tuesday at 11:48 PM EST.
Get from Myrtle Beach to Chicago
The journey takes about 1 day, 3 hours, and with fares starting at just $177, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Chicago?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 87445 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $211
Frequently asked questions about travelling from Myrtle Beach to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Myrtle Beach to Chicago?
The cheapest bus tickets from Myrtle Beach to Chicago start from $177. The average price for this route is around $240. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Myrtle Beach to Chicago?
The average bus travel time from Myrtle Beach to Chicago is 1d 3h, covering a distance of 1191 km. The quickest bus can get you there in 1d 2h and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Chicago route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Myrtle Beach to Chicago?
The earliest bus departs from Myrtle Beach to Chicago at 1:55pm. And the latest bus departs at 1:55pm.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Chicago?
A bus trip from Myrtle Beach to Chicago generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to Chicago was searched and found on Dec 25, 2025 with a price of $227To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Chicago, as early as possible.
You can expect to pay from $227 to $377 for a bus ticket from Myrtle Beach to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $227 which is on 2025-12-25.
