Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Opelika (4th Street Station) | Lafayette Bus Stop | No tags | ||||
FlixBus + Greyhound | Bus | Opelika (4th Street Station) | Lafayette Bus Stop | No tags | ||||
| Bus | Opelika (4th Street Station) | Lafayette Bus Stop | No tags | ||||
| Bus | Opelika (4th Street Station) | Lafayette Bus Stop | No tags |
Get from Opelika to Lafayette
The journey takes about 19 hours 25 minutes, and with fares starting at just $138, it presents an excellent value for a comfortable ride.
Where are the popular stops in Opelika and Lafayette?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Stops in Lafayette
- A
CityBus Center
N 3rd St & North St (Corner), Lafayette, IN 47901
Compare bus companies
Based on 87519 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $138
Frequently asked questions about travelling from Opelika to Lafayette, IN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Opelika to Lafayette?
The cheapest bus tickets from Opelika to Lafayette start from $138. The average price for this route is around $148. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Opelika to Lafayette?
The average bus travel time from Opelika to Lafayette is 19h 25m, covering a distance of 876 km. The quickest bus can get you there in 19h and is operated by Greyhound.
Which bus companies service the Opelika to Lafayette route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Opelika to Lafayette?
The earliest bus departs from Opelika to Lafayette at 9:00am. And the latest bus departs at 5:15pm.
What are the CO₂ emissions for the bus trip from Opelika to Lafayette?
A bus trip from Opelika to Lafayette generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Opelika to Lafayette, IN was searched and found on Feb 5, 2026 with a price of $128To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Opelika to Lafayette, IN, as early as possible.
You can expect to pay from $128 to $139 for a bus ticket from Opelika to Lafayette, IN based on the last 2 days. You can expect to find the cheapest price for the trip at $128 which is on 2026-02-05.
