Bus Tickets from Rochester, NY, US to St Louis

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TodayJul 9
TomorrowJul 10
from $156
FriJul 11
SatJul 12
from $155
SunJul 13
from $155
MonJul 14
TueJul 15
from $154
WedJul 16

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: July 10 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: July 11 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: July 11 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: Rochester
    Departure location: Rochester
    Arrival time: July 12 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Rochester to St Louis.

Bus
Average Price$153 - $232Average Duration1d 4h
29kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$193 - $1,064Average Duration20h 38m
107kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Rochester to St Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 1 day, 4 hours 55 minutes and with fares starting at just $153, it presents an excellent value for a comfortable ride.

3bus per day
1d 4hAverage Duration
$153Cheapest ticket
29kgCO₂ emissions

Bus Rochester to St. Louis: Trip Overview

Average ticket price$162
Average bus trip duration1d 4h
Number of daily buses3
Earliest bus departure6:10am
Distance727 miles (1171 km)
Latest bus departure11:50pm

Rochester to St Louis Bus

Busbud helps you find a bus from Rochester to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Rochester to St Louis will be provided by the most trusted bus companies.

Discover how much the bus trip from Rochester to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Rochester, NY, US - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/07
$148
07/08
No data
Today
No data
07/10
$148
07/11
No data
07/12
$148
07/13
$148
07/14
No data
busbud logoThe cheapest trip from Rochester to St. Louis was searched and found on Jul 7, 2025 with a price of $148

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester to St. Louis, as early as possible.

You can expect to pay from $148 to $148 for a bus ticket from Rochester to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $148 which is on 2025-07-10.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rochester and St Louis!

Much more than a mere vehicle taking you from Rochester to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rochester to St Louis will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rochester to St Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Rochester to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Rochester by bus?

Bus from Rochester to St. Louis

You can also go to St. Louis by train

Train from Rochester to St. Louis

Why choose Busbud?

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