How much is the bus ticket from Rochester to St. Louis?

The cheapest bus tickets from Rochester to St. Louis start from $111. The average price for this route is around $139. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Rochester to St. Louis?

The average bus trip duration from Rochester to St. Louis is 1d 5h, covering a distance of 727 miles (1172 km). The quickest bus can get you there in 1d 4h and is operated by FlixBus .

Which bus companies service the Rochester to St. Louis route?

Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Rochester to St. Louis?

The earliest bus departs from Rochester to St. Louis at 5:10am. And the latest bus departs at 11:35pm.

What are the CO₂ emissions for the bus trip from Rochester to St. Louis?

A bus trip from Rochester to St. Louis generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Rochester to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87463 reviews.

Which bus company has the best Wi-Fi from Rochester to St. Louis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Rochester to St. Louis?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Rochester to St. Louis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Rochester to St. Louis from $131 | Refundable Tickets

Previously seen trips

Next departures for Rochester to St. Louis on January 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	6:10am	Rochester	1d 1h	6:25am	Gateway Station	No tags
	Bus	6:55pm	Rochester	1d 5h	11:35pm	Gateway Station	No tags
Greyhound + FlixBus	Bus	11:50pm	Rochester	1d 16h	3:20pm	Gateway Station	No tags
FlixBus + Greyhound	Bus	11:50pm	Rochester	1d 16h	3:20pm	Gateway Station	No tags
	Bus	6:10am	Rochester	1d 1h	6:25am	Gateway Station	No tags

Compare 2 ways to go from Rochester to St. Louis

We recommend taking the train

Among the sustainable travel choices, the Train stands out as the good way to reach St. Louis. The journey takes about 1 day, 40 minutes and with fares starting at just $83, it presents an excellent value for a comfortable ride.

1train per day

1d Average Duration

727 milesDistance

107kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$111 - $295	Average Duration1d 5h	CO₂ emissions 29kg CO₂e
Train	Average Price$83 - $1,889	Average Duration1d	CO₂ emissions 107kg CO₂e

Where are the popular stops in Rochester and St. Louis?

Stops in Rochester

A
Bus Station
186 Cumberland St (Across from the Amtrak Terminal) , Rochester, NY 14605
Visit page Map
B
U of R
Rush Rhees Library, 755 Library Road, Rochester, NY 14627
Visit page Map
C
Rochester Institute of Technology
61 Lomb Memorial Dr, Rochester, NY 14623
Visit page Map

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page Map

Compare bus companies

Greyhound

3.5/587,492 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,983 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Rochester, NY, US to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Rochester to St. Louis?
The cheapest bus tickets from Rochester to St. Louis start from $111. The average price for this route is around $139. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rochester to St. Louis?
The average bus trip duration from Rochester to St. Louis is 1d 5h, covering a distance of 727 miles (1172 km). The quickest bus can get you there in 1d 4h and is operated by FlixBus.
Which bus companies service the Rochester to St. Louis route?
Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Rochester to St. Louis?
The earliest bus departs from Rochester to St. Louis at 5:10am. And the latest bus departs at 11:35pm.
What are the CO₂ emissions for the bus trip from Rochester to St. Louis?
A bus trip from Rochester to St. Louis generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Rochester to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Rochester to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Rochester to St. Louis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Rochester to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/08

$180

01/09

$281

Today

No data

01/11

$131

01/12

No data

01/13

$131

01/14

No data

01/15

$131

The cheapest trip from Rochester, NY, US to St. Louis was searched and found on Jan 11, 2026 with a price of $131

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to St. Louis, as early as possible.

You can expect to pay from $131 to $281 for a bus ticket from Rochester, NY, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $131 which is on 2026-01-11.