How much is the bus ticket from San Antonio to Lafayette?

The cheapest bus tickets from San Antonio to Lafayette start from $221. The average price for this route is around $276. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from San Antonio to Lafayette?

The average bus travel time from San Antonio to Lafayette is 1d 6h, covering a distance of 1614 km. The quickest bus can get you there in 1d 5h and is operated by Greyhound .

Which bus companies service the San Antonio to Lafayette route?

Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound , FlixBus .

What are the earliest and latest departure times for the bus from San Antonio to Lafayette?

The earliest bus departs from San Antonio to Lafayette at 1:30am. And the latest bus departs at 9:15pm.

What are the CO₂ emissions for the bus trip from San Antonio to Lafayette?

A bus trip from San Antonio to Lafayette generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from San Antonio to Lafayette?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87412 reviews.

Which bus company has the best Wi-Fi from San Antonio to Lafayette?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from San Antonio to Lafayette?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Antonio to Lafayette?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus San Antonio to Lafayette from $223 | Refundable Tickets

Next bus departures

Next departures for San Antonio to Lafayette on December 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	7:15pm	San Antonio Bus Station	1d 10h	6:25am	Lafayette Bus Stop	Cheapest
	Bus	12:35pm	San Antonio Bus Station	1d 5h	6:50pm	Lafayette Bus Stop	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 6h	1:50pm	Lafayette Bus Stop	No tags

Next departures for San Antonio to Lafayette on December 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 6h	1:50pm	Lafayette Bus Stop	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	1d 3h	6:25am	Lafayette Bus Stop	Fastest
	Bus	12:35pm	San Antonio Bus Station	1d 5h	6:50pm	Lafayette Bus Stop	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 8h	6:25am	Lafayette Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	2d 1h	9:50am	Lafayette Bus Stop	No tags

Next departures for San Antonio to Lafayette on December 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:35pm	San Antonio Bus Station	1d 5h	6:50pm	Lafayette Bus Stop	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	1d 3h	6:25am	Lafayette Bus Stop	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 6h	1:50pm	Lafayette Bus Stop	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 8h	6:25am	Lafayette Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	1d 10h	6:50pm	Lafayette Bus Stop	No tags

Next departures for San Antonio to Lafayette on December 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 6h	1:50pm	Lafayette Bus Stop	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	1d 3h	6:25am	Lafayette Bus Stop	Fastest
	Bus	12:35pm	San Antonio Bus Station	1d 5h	6:50pm	Lafayette Bus Stop	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 8h	6:25am	Lafayette Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	1d 10h	6:50pm	Lafayette Bus Stop	No tags

Next departures for San Antonio to Lafayette on December 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	1d 10h	6:50pm	Lafayette Bus Stop	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	1d 3h	6:25am	Lafayette Bus Stop	Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	6:05am	San Antonio Bus Station	1d 6h	1:50pm	Lafayette Bus Stop	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 8h	6:25am	Lafayette Bus Stop	No tags
	Bus	12:35pm	San Antonio Bus Station	1d 5h	6:50pm	Lafayette Bus Stop	No tags

Last refresh of the prices: Today at 3:10 PM CST.

Compare 2 ways to go from San Antonio to Lafayette

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Lafayette. The journey takes about 1 day, 6 hours 45 minutes, and with fares starting at just $221, it presents an excellent value for a comfortable ride.

5bus per day

1d 6hAverage Duration

1614 kmDistance

40kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$221 - $694	Average Duration1d 6h	CO₂ emissions 40kg CO₂e
Train	Average Price$294 - $1,476	Average Duration1d 14h	CO₂ emissions 147kg CO₂e

Where are the popular stops in San Antonio and Lafayette?

Stops in San Antonio

A
San Antonio Bus Station
500 N St Mary's St, San Antonio, TX 78205, USA
Visit page
B
Tornado I-35
7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
Visit page
C
San Antonio, TX
165 Bowie St, San Antonio, 78205
Visit page
D
4407 S PanAm Expy #101
4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Visit page

Stops in Lafayette

A
CityBus Center
N 3rd St & North St (Corner), Lafayette, IN 47901

Compare bus companies

Greyhound

3.5/587,433 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,624 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from San Antonio, US to Lafayette, IN by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from San Antonio to Lafayette?
The cheapest bus tickets from San Antonio to Lafayette start from $221. The average price for this route is around $276. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to Lafayette?
The average bus travel time from San Antonio to Lafayette is 1d 6h, covering a distance of 1614 km. The quickest bus can get you there in 1d 5h and is operated by Greyhound.
Which bus companies service the San Antonio to Lafayette route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from San Antonio to Lafayette?
The earliest bus departs from San Antonio to Lafayette at 1:30am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to Lafayette?
A bus trip from San Antonio to Lafayette generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from San Antonio to Lafayette?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from San Antonio to Lafayette?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from San Antonio to Lafayette?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to Lafayette?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-13

No data

12-14

No data

Today

No data

12-16

$466

12-17

$223

12-18

$253

12-19

$293

12-20

$294

The cheapest trip from San Antonio, US to Lafayette, IN was searched and found on Dec 17, 2025 with a price of $223

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Lafayette, IN, as early as possible.

You can expect to pay from $223 to $466 for a bus ticket from San Antonio, US to Lafayette, IN based on the last 2 days. You can expect to find the cheapest price for the trip at $223 which is on 2025-12-17.