Bus from San Antonio, US to Lafayette, IN: Tickets & Schedules
Next bus departures
Next departures for San Antonio to Lafayette on December 16
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
Cheapest
Bus
San Antonio Bus Station
Lafayette Bus Stop
Fastest
Next departures for San Antonio to Lafayette on December 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
Fastest
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Lafayette Bus Stop
No tags
Next departures for San Antonio to Lafayette on December 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
San Antonio Bus Station
Lafayette Bus Stop
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Lafayette Bus Stop
No tags
Next departures for San Antonio to Lafayette on December 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
Fastest
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Lafayette Bus Stop
No tags
Next departures for San Antonio to Lafayette on December 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Lafayette Bus Stop
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
Bus
San Antonio Bus Station
Lafayette Bus Stop
No tags
Last refresh of the prices: Yesterday at 3:10 PM CST.
Compare 2 ways to go from San Antonio to Lafayette
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Lafayette. The journey takes about 1 day, 6 hours 45 minutes and with fares starting at just $166, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from San Antonio, US to Lafayette, IN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Antonio to Lafayette?
The cheapest bus tickets from San Antonio to Lafayette start from $166. The average price for this route is around $201. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to Lafayette?
The average bus trip duration from San Antonio to Lafayette is 1d 6h, covering a distance of 999 miles (1612 km). The quickest bus can get you there in 1d 5h and is operated by Greyhound.
Which bus companies service the San Antonio to Lafayette route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from San Antonio to Lafayette?
The earliest bus departs from San Antonio to Lafayette at 1:30am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to Lafayette?
A bus trip from San Antonio to Lafayette generates an estimated 40 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Antonio to Lafayette?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from San Antonio to Lafayette?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from San Antonio to Lafayette?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to Lafayette?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/14
No data
12/15
No data
Today
$330
12/17
$158
12/18
$179
12/19
$207
12/20
$208
12/21
No data
The cheapest trip from San Antonio, US to Lafayette, IN was searched and found on Dec 17, 2025 with a price of $158
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Lafayette, IN, as early as possible.
You can expect to pay from $158 to $330 for a bus ticket from San Antonio, US to Lafayette, IN based on the last 2 days. You can expect to find the cheapest price for the trip at $158 which is on 2025-12-17.
What's the cheapest way to go from San Antonio, US to Lafayette, IN?
The bus is the cheapest travel choice for this destination
The cheapest trip from San Antonio, US to Lafayette, IN was searched and found on Dec 17, 2025 with a price of $158
The bus is the cheapest travel choice for this destination
