Bus Tickets from San Diego, CA, US to San Francisco, US

Next departures

Next departures for San Diego to San Francisco on October 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Amtrak
Santa Fe Depot
Mission St & Fremont StCheapest
Greyhound Lines, Inc.
Greyhound Bus Stop
San Francisco Bus StationFastest
FlixBus
San Diego (Old Town-FlixBus)
409 Townsend St, SFNo tags
FlixBus + Greyhound Lines, Inc.
San Diego (Old Town-FlixBus)
San Francisco Bus StationNo tags
FlixBus
UCSD Health La Jolla Station
409 Townsend St, SFNo tags

Last refresh of the prices: Today at 2:08 PM PDT.

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Bus San Diego, CA, US to San Francisco, US: Trip Overview

Average Ticket PriceUS$69
Average Bus Trip Duration15h
Number of daily buses11
Earliest bus departure6:45am
Distance720 km
Latest bus departure7:35pm

San Diego to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from San Diego to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to San Francisco from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to San Francisco from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Diego, CA, US - San Francisco, US

  1. What is the travel distance from San Diego to San Francisco?

    The distance between San Diego and San Francisco is around 739 km (458 miles).

  2. What are the departure and arrival locations for buses traveling from San Diego to San Francisco?

    Buses traveling this route start their trip at Mission Valley Sheraton, in San Diego, and end it at Hyde/Beach (Fisherman's Wharf), in San Francisco.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-07
US$100
10-08
US$115
Today
US$100
10-10
US$100
10-11
US$58
10-12
US$100
10-13
US$65
10-14
US$57
busbud logoThe cheapest trip from San Diego, CA, US to San Francisco, US was searched and found on Oct 14, 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to San Francisco, US, as early as possible.

You can expect to pay from US$57 to US$457 for a bus ticket from San Diego, CA, US to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$57 which is on 2025-10-14.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to San Francisco, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to San Francisco.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to San Francisco while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to San Diego, CA, US by bus?

Bus from San Francisco, US to San Diego, CA, US

Why choose Busbud?

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