Bus Tickets from Santa Fe (Santa Fe), AR to Buenos Aires, AR

Find affordable bus tickets from Santa Fe (Santa Fe), AR to Buenos Aires, AR with flexible options. Book your trip now

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TodayJun 6
from US$24
TomorrowJun 7
from US$16
SunJun 8
from US$18
MonJun 9
from US$23
TueJun 10
from US$23
WedJun 11
from US$23
ThuJun 12
from US$23
FriJun 13

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 7 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: June 7 at
    Destination city: Buenos Aires
    Destination location: Terminal Dellepiane
    Operated by: Via TacVia Tac
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 7 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: June 7 at
    Destination city: Buenos Aires
    Destination location: Terminal de Retiro
    Operated by: Via TacVia Tac
    Vehicle: BusDuration:
  • Departure time: June 7 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: June 7 at
    Destination city: Buenos Aires
    Destination location: Terminal de Retiro
    Operated by: ZenitZenit
    Vehicle: BusDuration:
  • Departure time: June 7 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: June 7 at
    Destination city: Buenos Aires
    Destination location: Terminal de Retiro
    Operated by: Flecha BusFlecha Bus
    Vehicle: BusDuration:
  • Departure time: June 7 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: June 7 at
    Destination city: Buenos Aires
    Destination location: Terminal de Retiro
    Operated by: La 20 de JunioLa 20 de Junio
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 9:07 PM -03.

Prices and availability are subject to change.

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Bus Santa Fe to Buenos Aires: Trip Overview

Average Ticket PriceUS$28
Average Bus Trip Duration6h 20m
Number of daily buses18
Earliest bus departure12:50am
Distance392 km
Latest bus departure11:55pm

Santa Fe to Buenos Aires Bus

With Busbud, comparing and booking tickets for a bus from Santa Fe to Buenos Aires is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Santa Fe to Buenos Aires from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Santa Fe to Buenos Aires, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Fe (Santa Fe), AR - Buenos Aires, AR

  1. How long is the bus ride from Santa Fe to Buenos Aires?

    The trip from Santa Fe to Buenos Aires will take on average 6h 20m. The fastest bus on this trip will get to Buenos Aires in 5h 20m

  2. How far is Santa Fe from Buenos Aires?

    The distance between Santa Fe and Buenos Aires is approximately 397 km (246 miles).

  3. What are the departure and arrival locations for buses traveling from Santa Fe to Buenos Aires?

    Buses departing from Estación Terminal de Ómnibius, Santa Fe in Santa Fe will take you to Terminal de Omnibus Retiro in Buenos Aires.

  4. What is the cheapest way to travel from Santa Fe to Buenos Aires?

    If you're on a budget, consider traveling by bus to Buenos Aires from Santa Fe; it tends to be more affordable. The ticket price for this bus starts at US$6, making this your best choice for this trip.

  5. How much does it cost to take the bus from Santa Fe to Buenos Aires?

    You can expect to pay around US$28 for the bus ride from Santa Fe to Buenos Aires.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-04
US$29
06-05
US$17
Today
US$15
06-07
US$15
06-08
US$16
06-09
US$21
06-10
US$21
06-11
US$21
busbud logoThe cheapest trip from Santa Fe to Buenos Aires was searched and found on Jun 6, 2025 with a price of US$15

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe to Buenos Aires, as early as possible.

You can expect to pay from US$15 to US$45 for a bus ticket from Santa Fe to Buenos Aires based on the last 2 days. You can expect to find the cheapest price for the trip at US$15 which is on 2025-06-07.

Usually Flechabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santa Fe to Buenos Aires.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Fe to Buenos Aires, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Fe to Buenos Aires that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Santa Fe to Buenos Aires, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Santa Fe by bus?

Bus from Santa Fe to Buenos Aires

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