Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Harrisburg Bus Station | No tags | ||||
| Bus | Gateway Station | Harrisburg Bus Station | No tags | ||||
| Bus | Gateway Station | Harrisburg Bus Station | No tags | ||||
| Bus | Gateway Station | Harrisburg Bus Station | No tags | ||||
| Bus | Gateway Station | Harrisburg Bus Station | No tags |
Compare 2 ways to go from St. Louis to Harrisburg
Among the sustainable travel choices, the Bus stands out as a good way to reach Harrisburg. The journey takes about 20 hours 5 minutes, and with fares starting at just $166, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Harrisburg?
Compare bus companies
Frequently asked questions about travelling from St. Louis to Harrisburg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Harrisburg?
The cheapest bus tickets from St. Louis to Harrisburg start from $166. The average price for this route is around $215. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Harrisburg?
The average bus travel time from St. Louis to Harrisburg is 20h 5m, covering a distance of 1158 km. The quickest bus can get you there in 19h 20m and is operated by Greyhound.
Which bus companies service the St. Louis to Harrisburg route?
What are the earliest and latest departure times for the bus from St. Louis to Harrisburg?
The earliest bus departs from St. Louis to Harrisburg at 2:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Harrisburg?
A bus trip from St. Louis to Harrisburg generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from St. Louis to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from St. Louis to Harrisburg?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from St. Louis to Harrisburg?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Harrisburg was searched and found on Jan 9, 2026 with a price of $176To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Harrisburg, as early as possible.
What's the cheapest way to go from St. Louis to Harrisburg?
The Bus is the cheapest travel choice for this destination
