What is the distance between Syracuse and Florence?

Syracuse and Florence are 1030 km (639 miles) apart.

What are the departure and arrival locations for buses traveling from Syracuse to Florence?

Buses departing from Regional Transportation Center in Syracuse will take you to Florence Bus Station in Florence.

Bus from Syracuse to Florence starting at $133 | Compare & Save up to 60%

Next bus departures

Next departures for Syracuse to Florence on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	3:00pm	Syracuse (Regional Transportation Center)	20h 45m	11:45am	Bus station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	9:25am	Syracuse (Regional Transportation Center)	20h 20m	5:45am	Florence, SC	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	1d 8h	5:45am	Florence, SC	No tags

Last refresh of the prices: Yesterday at 4:13 PM EST.

Compare 2 ways to go from Syracuse to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 20 hours 45 minutes, and with fares starting at just $133, it presents an excellent value for a comfortable ride.

2bus per day

20h 45mAverage Duration

1036 kmDistance

26kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$133 - $431	Average Duration20h 45m	CO₂ emissions 26kg CO₂e
Train	Average Price$316 - $910	Average Duration20h 4m	CO₂ emissions 94kg CO₂e

Where are the popular stops in Syracuse and Florence?

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
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B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Frequently asked questions about travelling from Syracuse, US to Florence, SC, US by bus

What is the distance between Syracuse and Florence?
Syracuse and Florence are 1030 km (639 miles) apart.
What are the departure and arrival locations for buses traveling from Syracuse to Florence?
Buses departing from Regional Transportation Center in Syracuse will take you to Florence Bus Station in Florence.