Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | 199 Spring Garden St. | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Philadelphia, 199 Spring Garden St | Fastest | ||||
 | Bus | Tupelo (Brothers Quick Stop) | 199 Spring Garden St. | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Philadelphia, 199 Spring Garden St | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Cherry Hill Mall | No tags |
Last refresh of the prices: Last Tuesday at 2:25 PM CST.
Get from Tupelo to Philadelphia
The journey takes about 1 day, 4 hours 25 minutes, and with fares starting at just $301, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87524 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $301
Frequently asked questions about travelling from Tupelo to Philadelphia, PA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Philadelphia?
The cheapest bus tickets from Tupelo to Philadelphia start from $301. The average price for this route is around $323. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Philadelphia?
The average bus travel time from Tupelo to Philadelphia is 1d 4h, covering a distance of 1366 km. The quickest bus can get you there in 1d 3h and is operated by Greyhound.
Which bus companies service the Tupelo to Philadelphia route?
Several major bus companies operate on this route with 14 buses available per day.
What are the earliest and latest departure times for the bus from Tupelo to Philadelphia?
The earliest bus departs from Tupelo to Philadelphia at 10:55am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Tupelo to Philadelphia?
A bus trip from Tupelo to Philadelphia generates an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Philadelphia, PA was searched and found on Mar 4, 2026 with a price of $197To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Philadelphia, PA, as early as possible.
You can expect to pay from $197 to $400 for a bus ticket from Tupelo to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $211 which is on 2026-03-06.
