Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | Tampa Bus Station | Cheapest | ||||
 | Bus | Bus station | Tampa Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Tampa Bus Station | No tags | ||||
| Bus | Florence, SC | Tampa Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | University of South Florida | No tags |
Last refresh of the prices: Today at 11:24 EST.
Compare 2 ways to travel from Florence to Tampa
Among the sustainable travel choices, the train stands out as a good way to reach Tampa. The journey takes about 18 hours 30 minutes and with fares starting at just £74, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Tampa?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
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Frequently asked questions about travelling by bus from Florence, SC, US to Tampa
What's the distance between Florence and Tampa by coach?
The journey from Florence to Tampa by coach covers an approximate distance of 464 miles (747 km).
What is the best way to go from Florence to Tampa without flying?
You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Tampa was searched and found on 20 Nov 2025 with a price of £78To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Tampa as early as possible.
You can expect to pay from £78 to £136 for a bus ticket from Florence, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at £82, which is on 2025-11-24.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Florence, SC, US to Tampa?
The bus is the cheapest travel choice for this destination
