What is the distance between Florence and Tampa?

Florence and Tampa are 464 miles (747 km) apart.

What are the departure and arrival stations when taking the bus from Florence to Tampa?

If you're headed to Tampa from Florence, chances are that your bus will depart from Florence Bus Station and arrive at Tampa 13th Avenue Bus Stop (McDonald's). These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

Bus Florence to Tampa from $80 | Refundable Tickets

Next bus departures

Next departures for Florence to Tampa on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:30pm	Bus station	1d 1h	6:10pm	Tampa Bus Station	Cheapest
	Bus	4:00pm	Bus station	14h	6:00am	Tampa Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	19h 20m	11:30am	Tampa Bus Station	No tags
	Bus	5:45am	Florence, SC	16h 40m	10:25pm	Tampa Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	21h 35m	9:30am	University of South Florida	No tags

Next departures for Florence to Tampa on November 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	14h	6:00am	Tampa Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	20h 50m	1:00pm	Tampa Bus Station	No tags
	Bus	4:30pm	Bus station	1d 1h	6:10pm	Tampa Bus Station	No tags
	Bus	5:45am	Florence, SC	16h 40m	10:25pm	Tampa Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	21h 35m	9:30am	University of South Florida	No tags

Next departures for Florence to Tampa on November 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	14h	6:00am	Tampa Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	19h 20m	11:30am	Tampa Bus Station	No tags
	Bus	4:30pm	Bus station	1d 1h	6:10pm	Tampa Bus Station	No tags
	Bus	5:45am	Florence, SC	16h 40m	10:25pm	Tampa Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	21h 35m	9:30am	University of South Florida	No tags

Last refresh of the prices: Last Saturday at 8:29 PM EST.

Compare 2 ways to go from Florence to Tampa

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Tampa. The journey takes about 18 hours 30 minutes and with fares starting at just $95, it presents an excellent value for a comfortable ride.

1train per day

18h 30mAverage Duration

460 milesDistance

67kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$58 - $229	Average Duration20h 50m	CO₂ emissions 18kg CO₂e
Train	Average Price$95 - $207	Average Duration18h 30m	CO₂ emissions 67kg CO₂e

Compare bus companies

FlixBus

3.5/511,378 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,382 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Florence and Tampa?

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Stops in Tampa

A - Tampa 13th Avenue Bus Stop (McDonald's)

B - Tampa USF, FL

C - Greyhound Station

D - E Sligh Ave

E - N Marion St & E Laurel St

F - Port of Tampa

Frequently asked questions about traveling from Florence, SC, US to Tampa by bus

What is the distance between Florence and Tampa?
What are the departure and arrival stations when taking the bus from Florence to Tampa?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/17

$102

11/18

$134

Today

$131

11/20

$99

11/21

$122

11/22

$116

11/23

$119

11/24

$105

The cheapest trip from Florence, SC, US to Tampa was searched and found on Nov 20, 2025 with a price of $99

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Tampa, as early as possible.

You can expect to pay from $99 to $145 for a bus ticket from Florence, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $99 which is on 2025-11-20.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.