Bus Tickets from Florence, SC, US to Tampa

Find affordable bus tickets from Florence, SC, US to Tampa with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 22
TomorrowJun 23
TueJun 24
WedJun 25
from $87
ThuJun 26
FriJun 27
from $94
SatJun 28
from $125
SunJun 29

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 25 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: June 26 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 25 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: June 25 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: June 25 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Florence to Tampa.

Bus
Average Price$68 - $159Average Duration11h 20m
18kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$89 - $244Average Duration18h 32m
67kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Tampa

Among the sustainable travel choices, the bus stands out as the good way to reach Tampa. The journey takes about 11 hours 20 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.

2bus per day
11h 20mAverage Duration
$68Cheapest ticket
18kgCO₂ emissions

Bus Florence to Tampa: Trip Overview

Average ticket price$100
Average bus trip duration11h 20m
Number of daily buses1.476190476190476
Earliest bus departure5:30am
Distance459 miles (740 km)
Latest bus departure12:55pm

Florence to Tampa Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Tampa.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Tampa.

Whether it is cheap bus tickets or more luxurious buses going to Tampa from Florence, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Florence, SC, US - Tampa

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/20
No data
06/21
$107
Today
$84
06/23
No data
06/24
No data
06/25
$79
06/26
No data
06/27
$86
busbud logoThe cheapest trip from Florence to Tampa was searched and found on Jun 25, 2025 with a price of $79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Tampa, as early as possible.

You can expect to pay from $79 to $107 for a bus ticket from Florence to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-06-25.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Tampa but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Florence to Tampa.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Tampa.

Make a music playlist for your bus ride from Florence to Tampa, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Florence to Tampa?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence by bus?

Bus from Florence to Tampa

You can also go to Tampa by train

Train from Florence to Tampa

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence

Popular Buses Connecting Tampa

Buses Leaving from Tampa

Buses Going to Tampa