Find coaches from La Crosse, WI to Chicago

Next departures

Next departures from La Crosse to Chicago on 9 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Greyhound Station
Ft Worth Bus StationCheapest
Expreso + Tornado Bus
Oklahoma City, (OK - Plaza Latina-Oklahoma City)
Fort Worth, (TX - TBC Fort Worth)Fastest
Greyhound Lines, Inc.
Greyhound Station
Ft Worth Bus StationNo tags
Tornado Bus + Tornado Elite
Oklahoma City, (OK - Plaza Latina-Oklahoma City)
Fort Worth, (TX - TBC Fort Worth)No tags
Greyhound Lines, Inc.
Greyhound Station
Ft Worth Bus StationNo tags

Last refresh of the prices: Yesterday at 20:58 CDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from La Crosse to Chicago

Bus
Average priceUS$184 - US$184Average duration17h 15m
9kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average priceUS$34 - US$149Average duration5h 8m
33kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from La Crosse to Chicago

Among the sustainable travel choices, the train stands out as a good way to reach Chicago. The journey takes about 5 hours 8 minutes and with fares starting at just US$34, it presents an excellent value for a comfortable ride.

3train per day
5h 8mAverage duration
US$34Cheapest ticket
33kgCO₂ emissions

Bus La Crosse, WI to Chicago: Trip Overview

Average ticket priceUS$184
Average bus trip duration17h 15m
Number of daily buses2
Earliest bus departure12:25
Distance226 miles
Latest bus departure12:50

La Crosse to Chicago Bus

Busbud helps you find a bus from La Crosse to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from La Crosse to Chicago from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from La Crosse, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip La Crosse, WI - Chicago

  1. What's the distance between La Crosse and Chicago by coach?

    The journey from La Crosse to Chicago by coach covers an approximate distance of 227 miles (367 km).

  2. How can I get from La Crosse to Chicago without driving?

    You can reach Chicago from La Crosse by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/10
No data
06/10
No data
Today
US$62
08/10
No data
09/10
US$41
10/10
No data
11/10
No data
12/10
No data
busbud logoThe cheapest trip from La Crosse, WI to Chicago was searched and found on 9 Oct 2025 with a price of US$41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Crosse, WI to Chicago as early as possible.

You can expect to pay from US$41 to US$105 for a bus ticket from La Crosse, WI to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$41, which is on 2025-10-09.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Crosse and Chicago!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from La Crosse to Chicago, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Crosse to Chicago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from La Crosse to Chicago.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

You can also go to Chicago by train

Train from La Crosse, WI to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting La Crosse

Buses Leaving from La Crosse

Buses Going to La Crosse

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago