Bus from New Orleans to Greenville, SC: Tickets & Timetables

Next bus departures

Next departures from New Orleans to Greenville on 9 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
New Orleans Bus Station
1116 Woodruff RdCheapestFastest
Greyhound Lines, Inc.Bus
New Orleans Bus Station
1116 Woodruff RdNo tags

Last refresh of the prices: Last Friday at 23:51 CST.

Compare 2 ways to travel from New Orleans to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 17 hours 5 minutes and with fares starting at just £68, it presents an excellent value for a comfortable ride.

3bus per day
17h 5mAverage duration
564 milesDistance
23kgCO₂ emissions
Average price£68 - £220Average duration17h 5m
23kg CO₂e
Average price£103 - £489Average duration16h 8m
82kg CO₂e

Frequently asked questions about travelling by bus from New Orleans to Greenville, SC

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from New Orleans to Greenville?

    The cheapest coach tickets from New Orleans to Greenville start from £68. The average price for this route is around £111. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from New Orleans to Greenville?

    The average bus journey time from New Orleans to Greenville is 17h 5m, covering a distance of 564 miles. The fastest bus can take you there in 12h 30m and is operated by Greyhound.

  3. Which bus companies service the New Orleans to Greenville route?

    Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, Amtrak.

  4. What is the earliest and latest departure time for the bus from New Orleans to Greenville?

    The earliest bus departs from New Orleans to Greenville at 13:00. And the latest bus departs at 23:15.

  5. What are the CO₂ emissions for the bus trip from New Orleans to Greenville?

    A bus journey from New Orleans to Greenville produces an estimated 23 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from New Orleans to Greenville?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.

  7. Which company has the best Wi-Fi from New Orleans to Greenville?

    Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company offers the most punctual service from New Orleans to Greenville?

    According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.

  9. Which bus company has the cleanest buses from New Orleans to Greenville?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
£112
06/12
£130
Today
£117
08/12
£65
09/12
£90
10/12
No data
11/12
£88
12/12
£90
busbud logoThe cheapest trip from New Orleans to Greenville, SC was searched and found on 8 Dec 2025 with a price of £65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Greenville, SC as early as possible.

You can expect to pay from £65 to £130 for a bus ticket from New Orleans to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £65, which is on 2025-12-08.

What's the cheapest way to go from New Orleans to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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