Find coaches from New Orleans to Greenville, SC

Next departures

Next departures from New Orleans to Greenville on 14 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
New Orleans Bus Station
1116 Woodruff RdCheapestFastest
Greyhound Lines, Inc.
New Orleans Bus Station
1116 Woodruff RdNo tags

Last refresh of the prices: Yesterday at 09:50 CDT.

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Compare 2 ways to travel from New Orleans to Greenville

Bus
Average priceUS$63 - US$137Average duration17h 5m
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$134 - US$472Average duration16h 8m
82kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from New Orleans to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 17 hours 5 minutes and with fares starting at just US$63, it presents an excellent value for a comfortable ride.

2bus per day
17h 5mAverage duration
US$63Cheapest ticket
23kgCO₂ emissions

Bus New Orleans to Greenville, SC: Trip Overview

Average ticket priceUS$91
Average bus trip duration17h 5m
Number of daily buses2
Earliest bus departure08:20
Distance564 miles
Latest bus departure23:15

New Orleans to Greenville Bus

With Busbud, comparing and booking tickets for a bus from New Orleans to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from New Orleans to Greenville from the most reliable bus companies operating this trip.

Discover how much the bus trip from New Orleans to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip New Orleans - Greenville, SC

  1. What's the distance between New Orleans and Greenville by coach?

    The journey from New Orleans to Greenville by coach covers an approximate distance of 561 miles (905 km).

  2. What is the best way to go from New Orleans to Greenville without flying?

    To travel from New Orleans to Greenville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/10
US$114
12/10
US$163
Today
US$144
14/10
US$124
15/10
US$62
16/10
US$56
17/10
US$71
18/10
US$64
busbud logoThe cheapest trip from New Orleans to Greenville, SC was searched and found on 16 Oct 2025 with a price of US$56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Greenville, SC as early as possible.

You can expect to pay from US$56 to US$207 for a bus ticket from New Orleans to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$56, which is on 2025-10-16.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from New Orleans to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Greenville, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from New Orleans to Greenville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from New Orleans to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from New Orleans to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to New Orleans by bus?

Bus from Greenville, SC to New Orleans

You can also go to Greenville, SC by train

Train from New Orleans to Greenville, SC

Why choose Busbud?

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