How much is the bus ticket from New Orleans to Greenville?

The cheapest bus tickets from New Orleans to Greenville start from $88. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from New Orleans to Greenville?

The average bus trip duration from New Orleans to Greenville is 17h 5m, covering a distance of 564 miles (910 km). The quickest bus can get you there in 12h 30m and is operated by Greyhound .

Which bus companies service the New Orleans to Greenville route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , Amtrak .

What is the earliest and latest departure time for the bus from New Orleans to Greenville?

The earliest bus departs from New Orleans to Greenville at 1:00pm. And the latest bus departs at 11:15pm.

What are the CO₂ emissions for the bus trip from New Orleans to Greenville?

A bus trip from New Orleans to Greenville generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from New Orleans to Greenville?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5597 reviews.

Which bus company has the best Wi-Fi from New Orleans to Greenville?

Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company has the most timely service from New Orleans to Greenville?

According to Busbud traveller reviews, the most timely bus company on this route is Amtrak , with a punctuality rating of 3.8 out of 5 stars.

Which bus company has the cleanest buses from New Orleans to Greenville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus New Orleans to Greenville from $84 | Refundable Tickets

Next bus departures

Next departures for New Orleans to Greenville on December 4
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	11:15pm	New Orleans Bus Station	21h 40m	9:55pm	1116 Woodruff Rd	Cheapest
	Bus	9:10pm	New Orleans Bus Station	12h 30m	10:40am	1116 Woodruff Rd	Fastest
	Bus	1:00pm	New Orleans Bus Station	17h 5m	7:05am	1116 Woodruff Rd	No tags

Next departures for New Orleans to Greenville on December 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	11:15pm	New Orleans Bus Station	21h 40m	9:55pm	1116 Woodruff Rd	Cheapest
	Bus	9:10pm	New Orleans Bus Station	12h 30m	10:40am	1116 Woodruff Rd	Fastest
	Bus	1:00pm	New Orleans Bus Station	17h 5m	7:05am	1116 Woodruff Rd	No tags

Next departures for New Orleans to Greenville on December 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	1:00pm	New Orleans Bus Station	17h 5m	7:05am	1116 Woodruff Rd	Cheapest
	Bus	9:10pm	New Orleans Bus Station	12h 30m	10:40am	1116 Woodruff Rd	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	11:15pm	New Orleans Bus Station	21h 40m	9:55pm	1116 Woodruff Rd	No tags

Next departures for New Orleans to Greenville on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	1:00pm	New Orleans Bus Station	17h 5m	7:05am	1116 Woodruff Rd	Cheapest
	Bus	9:10pm	New Orleans Bus Station	12h 30m	10:40am	1116 Woodruff Rd	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	11:15pm	New Orleans Bus Station	21h 40m	9:55pm	1116 Woodruff Rd	No tags

Last refresh of the prices: Yesterday at 1:54 PM CST.

Compare 2 ways to go from New Orleans to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 17 hours 5 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.

3bus per day

17h 5mAverage Duration

564 milesDistance

23kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$88 - $287	Average Duration17h 5m	CO₂ emissions 23kg CO₂e
Train	Average Price$134 - $636	Average Duration16h 8m	CO₂ emissions 82kg CO₂e

Where are the popular stops in New Orleans and Greenville?

Stops in New Orleans

A
Union Passenger Terminal
1001 Loyola Ave, New Orleans, LA 70113, USA
Visit page

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Compare bus companies

Greyhound

3.5/587,413 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Amtrak

4/55,623 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from New Orleans to Greenville, SC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from New Orleans to Greenville?
The cheapest bus tickets from New Orleans to Greenville start from $88. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from New Orleans to Greenville?
The average bus trip duration from New Orleans to Greenville is 17h 5m, covering a distance of 564 miles (910 km). The quickest bus can get you there in 12h 30m and is operated by Greyhound.
Which bus companies service the New Orleans to Greenville route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, Amtrak.
What is the earliest and latest departure time for the bus from New Orleans to Greenville?
The earliest bus departs from New Orleans to Greenville at 1:00pm. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from New Orleans to Greenville?
A bus trip from New Orleans to Greenville generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from New Orleans to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from New Orleans to Greenville?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from New Orleans to Greenville?
According to Busbud traveller reviews, the most timely bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from New Orleans to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/02

$141

12/03

$130

Today

$153

12/05

$121

12/06

$115

12/07

$108

12/08

$84

12/09

$103

The cheapest trip from New Orleans to Greenville, SC was searched and found on Dec 8, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Greenville, SC, as early as possible.

You can expect to pay from $84 to $179 for a bus ticket from New Orleans to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2025-12-08.