How far is Orlando from Florence?

Orlando and Florence are 405 miles (653 km) apart.

What are the departure and arrival stations when taking the bus from Orlando to Florence?

Most of the buses traveling from Orlando to Florence leave from Orlando Bus Station and arrive at Florence Bus Station. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Santa Maria Novella, Cattedrale Santa Maria del Fiore, Basilica di San Lorenzo, Museo degli Innocenti and Palazzo Pitti.

Bus Orlando to Florence from $57 | Refundable Tickets

Previously seen trips

Next departures for Orlando to Florence on November 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	4:45am	Orlando Bus Station	11h 20m	4:05pm	Bus station	No tags
	Bus	3:40pm	Orlando Bus Station	8h 19m	11:59pm	Florence, SC	No tags
FlixBus + Greyhound	Bus	10:30pm	Orlando Bus Station	1d 1h	11:59pm	Florence, SC	No tags
Greyhound + FlixBus	Bus	10:30pm	Orlando Bus Station	1d 1h	11:59pm	Florence, SC	No tags
Greyhound + FlixBus	Bus	4:45am	Orlando Bus Station	11h 20m	4:05pm	Bus station	No tags

Compare 2 ways to go from Orlando to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 9 hours 35 minutes and with fares starting at just $58, it presents an excellent value for a comfortable ride.

3bus per day

9h 35mAverage Duration

401 milesDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$58 - $199	Average Duration9h 35m	CO₂ emissions 16kg CO₂e
Train	Average Price$64 - $145	Average Duration9h 46m	CO₂ emissions 59kg CO₂e

Compare bus companies

FlixBus

3.5/511,361 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,380 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Orlando and Florence?

Stops in Orlando

A - Orlando Bus Station

B - Orlando RedCoach Station

C - Jet Set Express Terminal

D - Disney World

E - International Dr SuperTours Terminal

F - Seaworld Hotels

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions about traveling from Orlando to Florence, SC, US by bus

How far is Orlando from Florence?
What are the departure and arrival stations when taking the bus from Orlando to Florence?
What are the best sights and things to do in Florence?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/16

$89

11/17

$84

Today

No data

11/19

No data

11/20

No data

11/21

No data

11/22

$98

11/23

$104

The cheapest trip from Orlando to Florence, SC, US was searched and found on Nov 17, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Florence, SC, US, as early as possible.

You can expect to pay from $84 to $169 for a bus ticket from Orlando to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $98 which is on 2025-11-22.