How much is the bus ticket from Orlando to Florence?

The cheapest bus tickets from Orlando to Florence start from $85. The average price for this route is around $125. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Orlando to Florence?

The average bus travel time from Orlando to Florence is 9h 25m, covering a distance of 648 km. The quickest bus can get you there in 8h 25m and is operated by FlixBus .

Which bus companies service the Orlando to Florence route?

Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus , Greyhound .

What are the earliest and latest departure times for the bus from Orlando to Florence?

The earliest bus departs from Orlando to Florence at 4:00am. And the latest bus departs at 10:55pm.

What are the CO₂ emissions for the bus trip from Orlando to Florence?

A bus trip from Orlando to Florence generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Orlando to Florence?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 12208 reviews.

Which bus company has the best Wi-Fi from Orlando to Florence?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Orlando to Florence?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Orlando to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Orlando to Florence from $75 | Refundable Tickets

Previously seen trips

Next departures for Orlando to Florence on February 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	10:30pm	Orlando Bus Station	1d 1h	11:59pm	Florence, SC	No tags
Greyhound + FlixBus	Bus	10:30pm	Orlando Bus Station	1d 1h	11:59pm	Florence, SC	No tags
Greyhound + FlixBus	Bus	10:40pm	Orlando Bus Station	1d 1h	11:59pm	Florence, SC	No tags
FlixBus + Greyhound	Bus	10:40pm	Orlando Bus Station	1d 1h	11:59pm	Florence, SC	No tags
Greyhound + FlixBus	Bus	10:40pm	Orlando Bus Station	1d 1h	11:59pm	Florence, SC	No tags

View all departures

Compare 2 ways to go from Orlando to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 9 hours 25 minutes, and with fares starting at just $85, it presents an excellent value for a comfortable ride.

3bus per day

9h 25mAverage Duration

648 kmDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$85 - $426	Average Duration9h 25m	CO₂ emissions 16kg CO₂e
Train	Average Price$89 - $1,546	Average Duration9h 46m	CO₂ emissions 59kg CO₂e

Where are the popular stops in Orlando and Florence?

Stops in Orlando

A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805
Visit page
B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809
Visit page
C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
Visit page
D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F
Seaworld Hotels
10100 International Drive , Orlando, 32821

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/512,244 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wi‑Fi2.7

Greyhound

3.5/587,523 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wi‑Fi2.5

US bus companies:FlixBus, Greyhound, BlaBlaCar Bus, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Orlando to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Orlando to Florence?
The cheapest bus tickets from Orlando to Florence start from $85. The average price for this route is around $125. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Florence?
The average bus travel time from Orlando to Florence is 9h 25m, covering a distance of 648 km. The quickest bus can get you there in 8h 25m and is operated by FlixBus.
Which bus companies service the Orlando to Florence route?
Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus, Greyhound.
What are the earliest and latest departure times for the bus from Orlando to Florence?
The earliest bus departs from Orlando to Florence at 4:00am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Orlando to Florence?
A bus trip from Orlando to Florence generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Orlando to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12208 reviews.
Which bus company has the best Wi-Fi from Orlando to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Orlando to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

02-20

$115

02-21

$111

Today

$118

02-23

$111

02-24

$75

02-25

$80

02-26

$82

02-27

No data

The cheapest trip from Orlando to Florence, SC, US was searched and found on Feb 24, 2026 with a price of $75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Florence, SC, US, as early as possible.

You can expect to pay from $75 to $257 for a bus ticket from Orlando to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2026-02-24.