Find coaches from Panama City, US to Indianapolis

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Today2 Aug
from US$214
Tomorrow3 Aug
Mon4 Aug
Tue5 Aug
Wed6 Aug
Thu7 Aug
Fri8 Aug
Sat9 Aug

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 2 August at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: 4 August at
    Destination city: Indianapolis
    Destination location: Indianapolis Northeast
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 2 August at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: 4 August at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 2 August at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: 4 August at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 2 August at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: 4 August at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Panama City, US to Indianapolis: Trip Overview

Average ticket priceUS$185
Average bus trip duration22h 15m
Number of daily buses1
Earliest bus departure12:50
Distance661 miles

Panama City to Indianapolis Bus

Busbud helps you find a bus from Panama City to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to Indianapolis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Panama City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Panama City, US - Indianapolis

  1. How far is Indianapolis from Panama City by coach?

    The journey from Panama City to Indianapolis by coach covers an approximate distance of 664 miles (1071 km).

  2. Is there a way to reach Indianapolis from Panama City without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/07
No data
01/08
No data
Today
US$188
03/08
No data
04/08
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05/08
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06/08
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07/08
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busbud logoThe cheapest trip from Panama City, US to Indianapolis was searched and found on 2 Aug 2025 with a price of US$188

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Indianapolis as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Indianapolis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Indianapolis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Panama City to Indianapolis.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Indianapolis.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Panama City, US by bus?

Bus from Panama City, US to Indianapolis

Why choose Busbud?

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