Find coaches from Panama City, US to Louisville

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Bus Panama City to Louisville: Trip Overview

Average ticket priceUS$169
Average bus trip duration19h 45m
Number of daily buses1
Earliest bus departure12:50
Distance556 miles

Panama City to Louisville Bus

Busbud helps you find a bus from Panama City to Louisville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to Louisville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Panama City to Louisville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Panama City, US - Louisville

  1. How much is the coach fare from Panama City to Louisville?

    For coach travel from Panama City to Louisville, ticket prices typically start at US$169 and can reach a maximum of US$170. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long is the coach ride from Panama City to Louisville?

    The average duration for a trip from Panama City to Louisville by coach is around 19h 45m. If you're looking for the fastest trip, you can get there in just about 19h 45m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from Panama City to Louisville?

    The first coach to Louisville from Panama City departs at 12:50. Times and services may vary during weekends and holidays.

  4. How far is Louisville from Panama City by coach?

    The distance between Panama City and Louisville by coach is approximately 559 miles (901 km).

  5. What is the best way to go from Panama City to Louisville without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

  6. Is there am overnight coach from Panama City to Louisville?

    You can hop on buses departing from Panama City until 12:50 and reaching Louisville the following day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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US$171
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busbud logoThe cheapest trip from Panama City to Louisville was searched and found on 24 May 2025 with a price of US$171

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City to Louisville as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Louisville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Louisville, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Panama City to Louisville will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Panama City to Louisville while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Panama City by bus?

Bus from Panama City to Louisville

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