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- This trip is recommended because it is the: CheapestDeparture time: 22 July atDeparture city: PittsburghDeparture location: Pittsburgh Intermodal StationArrival time: 22 July atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: 22 July atDeparture city: PittsburghDeparture location: Pittsburgh Intermodal StationArrival time: 22 July atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 22 July atDeparture city: PittsburghDeparture location: Pittsburgh Intermodal StationArrival time: 22 July atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 22 July atDeparture city: PittsburghDeparture location: Pittsburgh Intermodal StationArrival time: 23 July atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: FlixBus
Vehicle: BusDuration:
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Compare 2 ways to travel from Pittsburgh to Chicago
Busbud recommends taking the bus from Pittsburgh to ChicagoAmong the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 13 hours 25 minutes and with fares starting at just US$59, it presents an excellent value for a comfortable ride.
Bus Pittsburgh to Chicago: Trip Overview
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Pittsburgh to Chicago Bus
Busbud helps you find a bus from Pittsburgh to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Pittsburgh to Chicago from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Chicago from Pittsburgh, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Pittsburgh and Chicago?
Frequently asked questions on the trip Pittsburgh - Chicago
What's the distance between Pittsburgh and Chicago by coach?
The journey from Pittsburgh to Chicago by coach covers an approximate distance of 410 miles (661 km).
What is the best way to go from Pittsburgh to Chicago without flying?
You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to Chicago was searched and found on 26 Jul 2025 with a price of US$64To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Chicago as early as possible.
You can expect to pay from US$64 to US$229 for a bus ticket from Pittsburgh to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$64, which is on 2025-07-26.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Pittsburgh and Chicago!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Pittsburgh to Chicago, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Pittsburgh to Chicago.
Tune out to the fine sounds of your best music playlist on your bus trip from Pittsburgh to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Pittsburgh to Chicago?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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