Bus Tickets from Pittsburgh to Chicago

Next departures

Next departures for Pittsburgh to Chicago on November 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    Pittsburgh Intermodal Station
    Downtown Greyhound StationCheapest
    Greyhound Lines, Inc.
      Pittsburgh Intermodal Station
      Downtown Greyhound StationFastest
      Greyhound Lines, Inc.
        Pittsburgh Intermodal Station
        Downtown Greyhound StationNo tags
        Greyhound Lines, Inc. + FlixBus
          Pittsburgh Intermodal Station
          Chicago 95Th & Dan RyanNo tags
          FlixBus
            Pittsburgh Intermodal Station
            Chicago 95Th & Dan RyanNo tags

            Last refresh of the prices: Today at 12:18 AM EST.

            Compare 2 ways to go from Pittsburgh to Chicago

            We recommend taking the train

            Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 9 hours 46 minutes and with fares starting at just $52, it presents an excellent value for a comfortable ride.

            1train per day
            9h 46mAverage Duration
            409 milesDistance
            60kgCO₂ emissions
            Average Price$52 - $172Average Duration13h 35m
            16kg CO₂e
            Average Price$52 - $129Average Duration9h 46m
            60kg CO₂e

            Frequently asked questions about traveling from Pittsburgh to Chicago by bus

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/07
            $79
            11/08
            $92
            Today
            $82
            11/10
            $68
            11/11
            $60
            11/12
            $58
            11/13
            $60
            11/14
            $64
            busbud logoThe cheapest trip from Pittsburgh to Chicago was searched and found on Nov 12, 2025 with a price of $58

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Chicago, as early as possible.

            You can expect to pay from $58 to $160 for a bus ticket from Pittsburgh to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $58 which is on 2025-11-12.

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