Find coaches from Portland, OR to Greenville, SC

Today3 Aug
Tomorrow4 Aug
from US$300
Tue5 Aug
Wed6 Aug
Thu7 Aug
Fri8 Aug
Sat9 Aug
Sun10 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 4 August at
    Departure city: Portland
    Departure location: Portland Curbside Bus Stop
    Arrival time: 8 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 4 August at
    Departure city: Portland
    Departure location: Portland Curbside Bus Stop
    Arrival time: 7 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 4 August at
    Departure city: Portland
    Departure location: Portland Curbside Bus Stop
    Arrival time: 7 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Portland to Greenville

Bus
Average priceUS$230 - US$353Average duration3d 2h
90kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$743 - US$743Average duration3d 9h
325kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Portland to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 3 days, 2 hours 10 minutes and with fares starting at just US$230, it presents an excellent value for a comfortable ride.

2bus per day
3d 2hAverage duration
US$230Cheapest ticket
90kgCO₂ emissions

Bus Portland, OR to Greenville, SC: Trip Overview

Average ticket priceUS$230
Average bus trip duration3d 2h
Number of daily buses2
Earliest bus departure02:20
Distance2224 miles
Latest bus departure20:00

Portland to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Portland to Greenville.

Bus service from Portland to Greenville will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Portland to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Portland, OR - Greenville, SC

  1. How far is Greenville from Portland by coach?

    The distance between Portland and Greenville by coach is approximately 2222 miles (3583 km).

  2. Is there a way to reach Greenville from Portland without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/08
No data
02/08
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Today
No data
04/08
US$348
05/08
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06/08
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07/08
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08/08
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busbud logoThe cheapest trip from Portland, OR to Greenville, SC was searched and found on 4 Aug 2025 with a price of US$348

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, OR to Greenville, SC as early as possible.

You can expect to pay from US$348 to US$348 for a bus ticket from Portland, OR to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$348, which is on 2025-08-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Portland to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Portland to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Portland to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Portland to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Portland, OR to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Portland, OR by bus?

Bus from Portland, OR to Greenville, SC

You can also go to Greenville, SC by train

Train from Portland, OR to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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