Find coaches from San Diego, CA, US to Chicago

Next departures

Next departures from San Diego to Chicago on 7 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
UCSD Health La Jolla Station
Chicago 95Th & Dan RyanCheapest
FlixBus + Greyhound Lines, Inc.
UCSD Health La Jolla Station
Downtown Greyhound StationFastest
FlixBus + Greyhound Lines, Inc.
San Diego (Old Town-FlixBus)
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.
Greyhound Bus Stop
Downtown Greyhound StationNo tags
FlixBus + Greyhound Lines, Inc.
San Diego (Old Town-FlixBus)
Downtown Greyhound StationNo tags

Last refresh of the prices: Yesterday at 23:36 PDT.

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Bus San Diego, CA, US to Chicago: Trip Overview

Average ticket priceUS$172
Average bus trip duration2d 7h
Number of daily buses37
Earliest bus departure06:45
Distance1725 miles
Latest bus departure19:35

San Diego to Chicago Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Chicago.

From cheap bus tickets to more luxurious buses travelling from San Diego to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Diego, CA, US - Chicago

  1. What's the distance between San Diego and Chicago by coach?

    The journey from San Diego to Chicago by coach covers an approximate distance of 1729 miles (2788 km).

  2. How can I travel from San Diego to Chicago avoiding air travel?

    To travel from San Diego to Chicago without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/10
US$354
05/10
US$272
Today
US$249
07/10
US$394
08/10
US$220
09/10
US$333
10/10
US$224
11/10
US$231
busbud logoThe cheapest trip from San Diego, CA, US to Chicago was searched and found on 8 Oct 2025 with a price of US$220

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Chicago as early as possible.

You can expect to pay from US$220 to US$483 for a bus ticket from San Diego, CA, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$220, which is on 2025-10-08.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Diego to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Chicago.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to San Diego, CA, US by bus?

Bus from Chicago to San Diego, CA, US

You can also go to Chicago by train

Train from San Diego, CA, US to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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