How far is San Diego from Chicago?

San Diego and Chicago are 1729 miles (2788 km) apart.

What are the departure and arrival stations when taking the bus from San Diego to Chicago?

Most of the buses traveling from San Diego to Chicago leave from Mission Valley Sheraton and arrive at Downtown Greyhound Station. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Chicago?

Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Museum of Science and Industry, Lincoln Park Conservatory, Architectural River Cruise, Willis Tower (Sears Tower) and Shedd Aquarium.

Bus San Diego to Chicago from $117 | Refundable Tickets

Next departures

Next departures for San Diego to Chicago on October 5
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 2h	6:35pm	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 1h	5:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	9:25am	San Diego (Old Town-FlixBus)	2d 10h	10:15pm	Downtown Greyhound Station	No tags
	6:45am	Greyhound Bus Stop	2d 8h	5:15pm	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	4:15pm	San Diego (Old Town-FlixBus)	2d 9h	4:10am	Downtown Greyhound Station	No tags

Next departures for San Diego to Chicago on October 6
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 1h	5:15pm	Downtown Greyhound Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	9:25am	San Diego (Old Town-FlixBus)	2d 10h	10:15pm	Downtown Greyhound Station	No tags
	6:45am	Greyhound Bus Stop	2d 8h	5:15pm	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	4:15pm	San Diego (Old Town-FlixBus)	2d 9h	4:10am	Downtown Greyhound Station	No tags
	7:35pm	Greyhound Bus Stop	2d 6h	4:10am	Downtown Greyhound Station	No tags

Next departures for San Diego to Chicago on October 7
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	6:45am	Greyhound Bus Stop	2d 7h	4:30pm	Downtown Greyhound Station	Cheapest
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 1h	5:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	7:35am	San Diego (Old Town-FlixBus)	2d 6h	4:30pm	Downtown Greyhound Station	No tags
	7:35pm	Greyhound Bus Stop	2d 6h	4:10am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	9:25am	San Diego (Old Town-FlixBus)	2d 6h	6:15pm	Downtown Greyhound Station	No tags

Next departures for San Diego to Chicago on October 8
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 1h	5:15pm	Downtown Greyhound Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	7:35am	San Diego (Old Town-FlixBus)	2d 6h	4:30pm	Downtown Greyhound Station	No tags
	7:35pm	Greyhound Bus Stop	2d 6h	4:10am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	9:25am	San Diego (Old Town-FlixBus)	2d 6h	6:15pm	Downtown Greyhound Station	No tags
	7:35pm	Greyhound Bus Stop	2d 10h	7:50am	537-517 W. Jackson Blvd	No tags

Next departures for San Diego to Chicago on October 9
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	7:35am	San Diego (Old Town-FlixBus)	2d 6h	3:55pm	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 1h	5:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	7:35am	San Diego (Old Town-FlixBus)	2d 6h	4:30pm	Downtown Greyhound Station	No tags
	7:35pm	Greyhound Bus Stop	2d 6h	4:10am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	9:25am	San Diego (Old Town-FlixBus)	2d 6h	6:15pm	Downtown Greyhound Station	No tags

Next departures for San Diego to Chicago on October 10
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	10:00am	Greyhound Bus Stop	2d 3h	3:55pm	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 1h	5:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	7:35am	San Diego (Old Town-FlixBus)	2d 6h	4:30pm	Downtown Greyhound Station	No tags
	7:35pm	Greyhound Bus Stop	2d 6h	4:10am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	12:15pm	San Diego (Old Town-FlixBus)	2d 4h	6:15pm	Downtown Greyhound Station	No tags

Next departures for San Diego to Chicago on October 11
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	10:00am	Greyhound Bus Stop	2d 4h	4:30pm	Downtown Greyhound Station	Cheapest
FlixBus + Greyhound Lines, Inc.	2:10pm	UCSD Health La Jolla Station	2d 1h	5:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	7:35am	San Diego (Old Town-FlixBus)	2d 6h	4:30pm	Downtown Greyhound Station	No tags
	7:35pm	Greyhound Bus Stop	2d 6h	4:10am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	12:15pm	San Diego (Old Town-FlixBus)	2d 4h	6:15pm	Downtown Greyhound Station	No tags

Last refresh of the prices: Yesterday at 11:55 PM PDT.

Bus San Diego, CA, US to Chicago: Trip Overview

Average ticket price$172

Average bus trip duration2d 7h

Number of daily buses37

Earliest bus departure6:45am

Distance1725 miles (2782 km)

Latest bus departure7:35pm

Compare bus companies

Greyhound

3.5/587,296 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/510,775 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Tufesa, Valley Transit, Senda Diamante

San Diego to Chicago Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Chicago.

From cheap bus tickets to more luxurious buses traveling from San Diego to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in San Diego and Chicago?

Stops in San Diego

A - Mission Valley Sheraton

B - Old Town Courtyard Marriot

C - Downtown Holiday Inn

D - Greyhound Station

E - Market St. & Park Blvd

F - San Ysidro McDonald's

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Frequently asked questions for your trip San Diego, CA, US - Chicago

How far is San Diego from Chicago?
What are the departure and arrival stations when taking the bus from San Diego to Chicago?
What are the best sights and things to do in Chicago?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10/02

$329

10/03

$426

Today

$354

10/05

$246

10/06

$148

10/07

$283

10/08

$214

10/09

$282

The cheapest trip from San Diego, CA, US to Chicago was searched and found on Oct 6, 2025 with a price of $148

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Chicago, as early as possible.

You can expect to pay from $148 to $483 for a bus ticket from San Diego, CA, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $148 which is on 2025-10-06.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Diego to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Chicago.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to San Diego, CA, US by bus?

Bus from Chicago to San Diego, CA, US

You can also go to Chicago by train

Train from San Diego, CA, US to Chicago

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from San Diego, CA, US to Chicago

Next departures

Bus San Diego, CA, US to Chicago: Trip Overview

Compare bus companies

San Diego to Chicago Bus

Where are the popular stops in San Diego and Chicago?

Frequently asked questions for your trip San Diego, CA, US - Chicago

How far is San Diego from Chicago?

What are the departure and arrival stations when taking the bus from San Diego to Chicago?

What are the best sights and things to do in Chicago?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to San Diego, CA, US by bus?

You can also go to Chicago by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago

Popular routes in this country

Popular airport transfers