Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal San Luis | Estación Terminal de Ómnibius, Santa Fe | Cheapest | ||||
 | Bus | Terminal San Luis | Estación Terminal de Ómnibius, Santa Fe | Fastest | ||||
| Bus | Terminal San Luis | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
| Bus | Terminal San Luis | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
 | Bus | Terminal San Luis | Estación Terminal de Ómnibius, Santa Fe | No tags |
Last refresh of the prices: Last Saturday at 22:56 -03.
Get from San Luis to Santa Fe
The journey takes about 12 hours 5 minutes, and with fares starting at just £31, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Luis and Santa Fe?
Stops in San Luis
- A
Estación de Interconexión Regional de Ómnibus de San Luis
Avenida del Fundador, s/n, 5700 San Luis - BTerminal de San Luis, Av. del Fundador y Av. Santos Ortiz
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
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Frequently asked questions about travelling by bus from San Luis, AR to Santa Fe, AR
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from San Luis to Santa Fe?
The cheapest coach tickets from San Luis to Santa Fe start from £31. The average price for this route is around £41. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from San Luis to Santa Fe?
The average bus journey time from San Luis to Santa Fe is 12h 5m, covering a distance of 345 miles. The fastest bus can take you there in 10h 40m and is operated by Flechabus.
Which bus companies service the San Luis to Santa Fe route?
Several major bus companies operate on this route with 2 buses available per day, including services from 20 de Junio, Andesmar, Flechabus, Tramat.
What is the earliest and latest departure time for the bus from San Luis to Santa Fe?
The earliest bus departs from San Luis to Santa Fe at 01:20. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from San Luis to Santa Fe?
A bus journey from San Luis to Santa Fe produces an estimated 14 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from San Luis to Santa Fe?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 590 reviews.
Which company has the best Wi-Fi from San Luis to Santa Fe?
Based on Busbud reviews, the bus company 20 de Junio has the best Wi-Fi rating with a score of 2.3.
Which bus company offers the most punctual service from San Luis to Santa Fe?
According to Busbud traveller reviews, the most punctual bus company on this route is 20 de Junio, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from San Luis to Santa Fe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Luis, AR to Santa Fe, AR was searched and found on 10 Jan 2026 with a price of £31To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis, AR to Santa Fe, AR as early as possible.
You can expect to pay from £31 to £47 for a bus ticket from San Luis, AR to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at £31, which is on 2026-01-10.
