Find coaches from Knoxville, TN to Syracuse, US

Previously seen journeys

Next departures from Knoxville to Syracuse on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Knoxville Bus Station
Syracuse (Regional Transportation Center)No tags
Greyhound
Knoxville Bus Station
Syracuse (Regional Transportation Center)No tags
Greyhound
Knoxville Bus Station
Syracuse (Regional Transportation Center)No tags
Greyhound
Knoxville Bus Station
Syracuse (Regional Transportation Center)No tags
Greyhound
Knoxville Bus Station
Syracuse (Regional Transportation Center)No tags

Accepted payments

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Get from Knoxville to Syracuse

busbud logoThis route is served by bus only

The journey takes about 22 hours 25 minutes, and with fares starting at just US$145, it presents an excellent value for a comfortable ride.

1bus per day
22h 25mAverage duration
1027 kmDistance
26kgCO₂ emissions

Bus Knoxville, TN to Syracuse, US: Trip Overview

Average ticket priceUS$145
Average bus trip duration22h 25m
Number of daily buses1
Earliest bus departure22:00
Distance1027 km

Knoxville to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Knoxville to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Knoxville to Syracuse from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Syracuse from Knoxville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Knoxville, TN - Syracuse, US

  1. How much does a bus ticket from Knoxville to Syracuse cost?

    The bus ticket price from Knoxville to Syracuse starts at US$145. The best way to find cheap bus tickets from Knoxville to Syracuse is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Knoxville to Syracuse?

    The average travel time between Knoxville and Syracuse is around 22h 25m, although the fastest bus will take about 22h 25m. This is the time it takes to travel the 1033 km that separates the two cities.

  3. How many daily bus connections are there between Knoxville and Syracuse?

    The number of buses from Knoxville to Syracuse can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Knoxville to Syracuse by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Knoxville to Syracuse?

    When taking the bus from Knoxville to Syracuse, you can travel comfortably and safely with Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
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29/10
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Today
No data
31/10
US$137
01/11
No data
02/11
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03/11
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04/11
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busbud logoThe cheapest trip from Knoxville, TN to Syracuse, US was searched and found on 31 Oct 2025 with a price of US$137

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Syracuse, US as early as possible.

You can expect to pay from US$137 to US$137 for a bus ticket from Knoxville, TN to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$137, which is on 2025-10-31.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Knoxville to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Syracuse, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Syracuse.

Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Syracuse while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Knoxville, TN by bus?

Bus from Syracuse, US to Knoxville, TN

Why choose Busbud?

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