Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Altoona Station | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Altoona Station | Downtown Transit Center | No tags | ||||
| Bus | Altoona Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Altoona Station | Downtown Transit Center | No tags | ||||
| Bus | Altoona Station | Indianapolis Bus Station | No tags |
Compare 2 ways to go from Altoona to Indianapolis
Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 20 hours 55 minutes and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Altoona to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Altoona to Indianapolis?
The cheapest bus tickets from Altoona to Indianapolis start from $99. The average price for this route is around $126. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Altoona to Indianapolis?
The average bus trip duration from Altoona to Indianapolis is 20h 55m, covering a distance of 412 miles (664 km). The quickest bus can get you there in 13h 30m and is operated by Greyhound.
Which bus companies service the Altoona to Indianapolis route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Altoona to Indianapolis?
The earliest bus departs from Altoona to Indianapolis at 12:50pm. And the latest bus departs at 2:30pm.
What are the CO₂ emissions for the bus trip from Altoona to Indianapolis?
A bus trip from Altoona to Indianapolis generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Altoona to Indianapolis was searched and found on Dec 14, 2025 with a price of $115To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Altoona to Indianapolis, as early as possible.
You can expect to pay from $115 to $164 for a bus ticket from Altoona to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $136 which is on 2025-12-15.
What's the cheapest way to go from Altoona to Indianapolis?
The bus is the cheapest travel choice for this destination
