Bus Tickets from Big Pine Key to Panama City, US

Previously seen trips

Next departures for Big Pine Key to Panama City on October 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Big Pine Key, FL
Panama City Beach StationNo tags
Greyhound
Big Pine Key, FL
Panama City Beach StationNo tags
Greyhound
Big Pine Key, FL
Panama City Beach StationNo tags
Greyhound
Big Pine Key, FL
Panama City Beach StationNo tags
Greyhound
Big Pine Key, FL
Panama City Beach StationNo tags

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Bus Big Pine Key to Panama City, US: Trip Overview

Average ticket price$146
Average bus trip duration21h
Number of daily buses1
Earliest bus departure5:40pm
Distance467 miles (752 km)

Big Pine Key to Panama City Bus

Busbud helps you find a bus from Big Pine Key to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Big Pine Key to Panama City.

From cheap bus tickets to more luxurious buses traveling from Big Pine Key to Panama City, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Big Pine Key - Panama City, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/03
No data
10/04
$138
Today
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10/06
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10/07
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10/08
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10/09
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10/10
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busbud logoThe cheapest trip from Big Pine Key to Panama City, US was searched and found on Oct 4, 2025 with a price of $138

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Big Pine Key to Panama City, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Big Pine Key and Panama City!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Big Pine Key to Panama City.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Big Pine Key to Panama City that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Big Pine Key to Panama City while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Big Pine Key by bus?

Bus from Panama City, US to Big Pine Key

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