Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
 | Bus | BILOXI | Tupelo (Brothers Quick Stop) | ||||
| Bus | BILOXI | Tupelo (Brothers Quick Stop) | ||||
| Bus | BILOXI | Tupelo (Brothers Quick Stop) | ||||
| Bus | BILOXI | Tupelo (Brothers Quick Stop) | ||||
| Bus | BILOXI | Tupelo (Brothers Quick Stop) |
Get from Biloxi to Tupelo
The journey takes about 11 hours 40 minutes and with fares starting at just R 1 251, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Biloxi to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Biloxi to Tupelo?
The cheapest bus tickets from Biloxi to Tupelo start from R 1 251. The average price for this route is around R 1 346. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Biloxi to Tupelo?
The average bus trip duration from Biloxi to Tupelo is 11h 40m, covering a distance of 265 miles (428 km). The quickest bus can get you there in 11h 40m and is operated by Greyhound.
Which bus companies service the Biloxi to Tupelo route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Biloxi to Tupelo?
The earliest bus departs from Biloxi to Tupelo at 9:55am. And the latest bus departs at 9:55am.
What are the CO₂ emissions for the bus trip from Biloxi to Tupelo?
A bus trip from Biloxi to Tupelo generates an estimated 10.677375 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Biloxi to Tupelo was searched and found on Jul 30, 2026 with a price of R 1 421To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Biloxi to Tupelo, as early as possible.
You can expect to pay from R 1 421 to R 1 679 for a bus ticket from Biloxi to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 421 which is on 2026-07-30.
