Bus from Buffalo, NY to Charlotte, NC: Tickets & Schedules

Next bus departures

Next departures for Buffalo to Charlotte on December 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Niagara Frontier Transportation Authority
Charlotte (Freedom Dr)Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Buffalo (BUF) Airport
Charlotte Bus StationFastest
FlixBus + Greyhound Lines, Inc.
Bus
Niagara Frontier Transportation Authority
Charlotte Bus StationNo tags
FlixBusBus
Buffalo (BUF) Airport
Charlotte (Freedom Dr)No tags
Greyhound Lines, Inc. + FlixBus
Bus
Niagara Frontier Transportation Authority
Charlotte Bus StationNo tags

Last refresh of the prices: Last Wednesday at 7:36 AM EST.

Compare 2 ways to go from Buffalo to Charlotte

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Charlotte. The journey takes about 22 hours 2 minutes and with fares starting at just $187, it presents an excellent value for a comfortable ride.

2train per day
22h 2mAverage Duration
537 milesDistance
79kgCO₂ emissions
Average Price$99 - $476Average Duration1d
22kg CO₂e
Average Price$187 - $1,470Average Duration22h 2m
79kg CO₂e

Frequently asked questions about traveling from Buffalo, NY to Charlotte, NC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Buffalo to Charlotte?

    The cheapest bus tickets from Buffalo to Charlotte start from $99. The average price for this route is around $152. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Buffalo to Charlotte?

    The average bus trip duration from Buffalo to Charlotte is 1d , covering a distance of 543 miles (876 km). The quickest bus can get you there in 21h 30m and is operated by FlixBus.

  3. Which bus companies service the Buffalo to Charlotte route?

    Several major bus companies operate on this route with 13 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Buffalo to Charlotte?

    The earliest bus departs from Buffalo to Charlotte at 12:55am. And the latest bus departs at 11:59pm.

  5. What are the CO₂ emissions for the bus trip from Buffalo to Charlotte?

    A bus trip from Buffalo to Charlotte generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Buffalo to Charlotte?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from Buffalo to Charlotte?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Buffalo to Charlotte?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Buffalo to Charlotte?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/27
$126
11/28
$266
Today
$252
11/30
$185
12/01
No data
12/02
$130
12/03
$105
12/04
$110
busbud logoThe cheapest trip from Buffalo, NY to Charlotte, NC was searched and found on Dec 3, 2025 with a price of $105

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Charlotte, NC, as early as possible.

You can expect to pay from $105 to $347 for a bus ticket from Buffalo, NY to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $105 which is on 2025-12-03.

What's the cheapest way to go from Buffalo, NY to Charlotte, NC?

busbud logoThe bus is the cheapest travel choice for this destination

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