Next departures for Charlotte to Indianapolis on January 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Charlotte Bus Station
Indianapolis Bus Station
CheapestFastest
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Charlotte Bus Station
Downtown Transit Center
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Charlotte (Freedom Dr)
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Charlotte (Freedom Dr)
Indianapolis Bus Station
No tags
Next departures for Charlotte to Indianapolis on January 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Charlotte Bus Station
Indianapolis Bus Station
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte (Uptown)
Downtown Transit Center
No tags
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Next departures for Charlotte to Indianapolis on January 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Charlotte Bus Station
Indianapolis Bus Station
Cheapest
Bus
Charlotte Bus Station
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte (Uptown)
Downtown Transit Center
No tags
Next departures for Charlotte to Indianapolis on January 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Charlotte Bus Station
Downtown Transit Center
Cheapest
Bus
Charlotte Bus Station
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Next departures for Charlotte to Indianapolis on January 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Charlotte Bus Station
Downtown Transit Center
Cheapest
Bus
Charlotte Bus Station
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte Bus Station
Indianapolis Bus Station
No tags
Bus
Charlotte Bus Station
Downtown Transit Center
No tags
Last refresh of the prices: Last Friday at 11:14 AM EST.
Compare 2 ways to go from Charlotte to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the Bus stands out as the good way to reach Indianapolis. The journey takes about 21 hours 50 minutes and with fares starting at just $89, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Charlotte, NC to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charlotte to Indianapolis?
The cheapest bus tickets from Charlotte to Indianapolis start from $89. The average price for this route is around $129. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charlotte to Indianapolis?
The average bus trip duration from Charlotte to Indianapolis is 21h 50m, covering a distance of 424 miles (684 km). The quickest bus can get you there in 15h 50m and is operated by Greyhound.
Which bus companies service the Charlotte to Indianapolis route?
Several major bus companies operate on this route with 19 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Charlotte to Indianapolis?
The earliest bus departs from Charlotte to Indianapolis at 12:55am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Charlotte to Indianapolis?
A bus trip from Charlotte to Indianapolis generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Charlotte to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Charlotte to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Charlotte to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charlotte to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
01/16
$162
01/17
$168
Today
$142
01/19
$132
01/20
$113
01/21
$110
01/22
No data
01/23
$113
The cheapest trip from Charlotte, NC to Indianapolis was searched and found on Jan 21, 2026 with a price of $110
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to Indianapolis, as early as possible.
You can expect to pay from $110 to $183 for a bus ticket from Charlotte, NC to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2026-01-21.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Charlotte, NC to Indianapolis?
The Bus is the cheapest travel choice for this destination