Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Charlotte (Uptown) | Knoxville Bus Station | No tags | |||||
Greyhound + FlixBus | Charlotte (Freedom Dr) | Knoxville Bus Station | No tags | |||||
FlixBus + Greyhound | Charlotte (Freedom Dr) | Knoxville Bus Station | No tags | |||||
Greyhound + FlixBus | Charlotte (Freedom Dr) | Knoxville Bus Station | No tags | |||||
FlixBus + Greyhound | Charlotte (Freedom Dr) | Knoxville Bus Station | No tags |
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Get from Charlotte to Knoxville
The journey takes about 12 hours 55 minutes and with fares starting at just $48, it presents an excellent value for a comfortable ride.
Bus Charlotte, NC to Knoxville, TN: Trip Overview
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Charlotte to Knoxville Bus
With Busbud, comparing and booking tickets for a bus from Charlotte to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Charlotte to Knoxville will be provided by the most trusted bus companies.
Discover how much the bus trip from Charlotte to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Charlotte and Knoxville?
Frequently asked questions for your trip Charlotte, NC - Knoxville, TN
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charlotte, NC to Knoxville, TN was searched and found on Nov 5, 2025 with a price of $48To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to Knoxville, TN, as early as possible.
You can expect to pay from $48 to $103 for a bus ticket from Charlotte, NC to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2025-11-05.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Charlotte to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Charlotte to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Charlotte to Knoxville will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Charlotte to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Charlotte
Buses Leaving from Charlotte
- Bus from Charlotte to Augusta
- Bus Charlotte - Windsor
- Charlotte - Beaumont
- Bus from Charlotte to New York City
- Bus Charlotte - Olympia
- Charlotte - Miami
- Bus from Charlotte to Atlanta
- Bus Charlotte - Asheville
- Charlotte - Washington
- Bus from Charlotte to Greenville
- Bus Charlotte - Raleigh
- Charlotte - Orlando
- Bus from Charlotte to Blacksburg
- Bus Charlotte - Winston-Salem
- Charlotte - Wilmington
Buses Going to Charlotte
- Bus from McKinney to Charlotte
- Bus York - Charlotte
- Marathon - Charlotte
- Bus from Hamilton to Charlotte
- Bus Winston-Salem - Charlotte
- Boston - Charlotte
- Bus from New York City to Charlotte
- Bus Atlanta - Charlotte
- Washington - Charlotte
- Bus from Blacksburg to Charlotte
- Bus Asheville - Charlotte
- Greenville - Charlotte
- Bus from Raleigh to Charlotte
- Bus Miami - Charlotte
- Baltimore - Charlotte
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Tampa
- Bus from Knoxville to Jackson
- Bus Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Hartford - Knoxville
- New York City - Knoxville
- Bus from Louisville to Knoxville
- Bus Cincinnati - Knoxville
- Lexington - Knoxville
- Bus from Greenville to Knoxville
- Bus Dallas - Knoxville
- Cookeville - Knoxville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio