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- This trip is recommended because it is: Cheapest + FastestDeparture time: July 18 atDeparture city: CharlottesvilleDeparture location: Charlottesville Union StationArrival time: July 18 atDestination city: KnoxvilleDestination location: Knoxville Bus StationOperated by: Greyhound Lines, Inc.
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Bus Charlottesville to Knoxville: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Charlottesville to Knoxville Bus
With Busbud, comparing and booking tickets for a bus from Charlottesville to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Charlottesville to Knoxville will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Charlottesville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Charlottesville and Knoxville?
Frequently asked questions for your trip Charlottesville - Knoxville, TN
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charlottesville to Knoxville was searched and found on Jul 17, 2025 with a price of $54To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlottesville to Knoxville, as early as possible.
You can expect to pay from $54 to $61 for a bus ticket from Charlottesville to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2025-07-18.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Charlottesville to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Charlottesville to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charlottesville to Knoxville.
Tune out to the fine sounds of your best music playlist on your bus trip from Charlottesville to Knoxville while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
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Popular Buses Connecting Charlottesville
Buses Leaving from Charlottesville
- Bus from Charlottesville to Richmond
- Bus Charlottesville - Nashville
- Charlottesville - Atlanta
- Bus from Charlottesville to Boston
- Bus Charlottesville - Blacksburg
- Charlottesville - Washington
- Bus from Charlottesville to Virginia Beach
- Bus Charlottesville - Norfolk
- Charlottesville - New York City
- Bus from Charlottesville to Williamsburg
Buses Going to Charlottesville
- Bus from Hamilton to Charlottesville
- Bus Lynchburg - Charlottesville
- Charlotte - Charlottesville
- Bus from Williamsburg to Charlottesville
- Bus Norfolk - Charlottesville
- Blacksburg - Charlottesville
- Bus from Richmond to Charlottesville
- Bus Washington - Charlottesville
- New York City - Charlottesville
- Bus from Alexandria to Charlottesville
- Bus Roanoke - Charlottesville
- Staunton - Charlottesville
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Orlando
- Bus from Knoxville to Lexington
- Bus Knoxville - Chicago
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Jackson
- Bus from Knoxville to Cincinnati
- Bus Knoxville - Dallas
- Knoxville - Greenville
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus New York City - Knoxville
- Greenville - Knoxville
- Bus from Louisville to Knoxville
- Bus Cookeville - Knoxville
- Lexington - Knoxville
- Bus from Dallas to Knoxville
- Bus Los Angeles - Knoxville
- Baltimore - Knoxville