Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Durham Greyhound Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
| Durham Greyhound Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
FlixBus + Greyhound | Durham Greyhound Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
Greyhound + FlixBus | Durham Greyhound Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
Greyhound + FlixBus | Durham Greyhound Bus Station | 4565 Gaynor Ave, North Charleston | No tags |
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Compare 2 ways to go from Durham to Charleston
Among the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 10 hours 3 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.
Bus Durham, NC, US to Charleston, SC, US: Trip Overview
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Durham to Charleston Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Durham to Charleston.
Bus service from Durham to Charleston will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Charleston from Durham, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Durham and Charleston?
Frequently asked questions for your trip Durham, NC, US - Charleston, SC, US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Charleston, SC, US was searched and found on Nov 6, 2025 with a price of $57To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Charleston, SC, US, as early as possible.
You can expect to pay from $57 to $61 for a bus ticket from Durham, NC, US to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $57 which is on 2025-11-06.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Durham to Charleston but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Durham to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Charleston.
Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Charleston while indulging in miles on end of beautiful scenic views.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
What's the cheapest way to go from Durham, NC, US to Charleston, SC, US?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Popular Buses Connecting Durham
Buses Leaving from Durham
- Bus from Durham to Greensboro
- Bus Durham - York
- Durham - Atlanta
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- Bus Durham - Winston-Salem
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- Bus Durham - New York City
- Durham - Miami
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- Durham - Richmond
- Bus from Durham to Burlington
- Bus Durham - Baltimore
- Durham - Henderson
Buses Going to Durham
- Bus from Charlotte to Durham
- Bus Asheville - Durham
- Atlanta - Durham
- Bus from McKinney to Durham
- Bus Corning - Durham
- Toronto - Durham
- Bus from New York City to Durham
- Bus Washington - Durham
- Richmond - Durham
- Bus from Fayetteville to Durham
- Bus Baltimore - Durham
- Burlington - Durham
- Bus from Winston-Salem to Durham
- Bus Raleigh - Durham
- Charlottesville - Durham
Popular Buses Connecting Charleston
Buses Leaving from Charleston
- Bus from Charleston to Baltimore
- Bus Charleston - Tulsa
- Charleston - Atlanta
- Bus from Charleston to Fort Worth
- Bus Charleston - Jacksonville
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- Bus Charleston - Greenville
- Charleston - Charlotte
- Bus from Charleston to Orlando
- Bus Charleston - New York City
- Charleston - Raleigh
- Bus from Charleston to Florence
- Bus Charleston - Greensboro
- Charleston - Washington
Buses Going to Charleston
- Bus from Myrtle Beach to Charleston
- Bus Baltimore - Charleston
- Boston - Charleston
- Bus from Greenville to Charleston
- Bus Raleigh - Charleston
- Nashville - Charleston
- Bus from Savannah to Charleston
- Bus Atlanta - Charleston
- Orlando - Charleston
- Bus from New York City to Charleston
- Bus Charlotte - Charleston
- Miami - Charleston
- Bus from Jacksonville to Charleston
- Bus Tampa - Charleston
- Philadelphia - Charleston
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
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- Miami - Tampa
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- Houston - Austin
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